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首页> 外文期刊>Journal of Clinical Microbiology >Prevalence and Genetic Diversity of Human Astroviruses in Mexican Children with Symptomatic and Asymptomatic Infections
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Prevalence and Genetic Diversity of Human Astroviruses in Mexican Children with Symptomatic and Asymptomatic Infections

机译:墨西哥儿童有症状和无症状感染的人类星状病毒的流行和遗传多样性

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The prevalence and type diversity of human astroviruses (HAstV) in children with symptomatic and asymptomatic infections were determined in five localities of Mexico. HAstV were detected in 4.6 (24 of 522) and 2.6% (11 of 428) of children with and without diarrhea, respectively. Genotyping of the detected strains showed that at least seven (types 1 to 4 and 6 to 8) of the eight known HAstV types circulated in Mexico between October 1994 and March 1995. HAstV types 1 and 3 were the most prevalent in children with diarrhea, although they were not found in all localities studied. HAstV type 8 was found in Mexico City, Monterrey, and Mérida; in the last it was as prevalent (40%) as type 1 viruses, indicating that this astrovirus type is more common than previously recognized. A correlation between the HAstV infecting type and the presence or absence of diarrheic symptoms was not observed. Enteric adenoviruses were also studied, and they were found to be present in 2.3 (12 of 522) and 1.4% (6 of 428) of symptomatic and asymptomatic children, respectively.
机译:在墨西哥的五个地区,确定了有症状和无症状感染儿童的人类星状病毒(HAstV)的患病率和类型多样性。分别在有腹泻和没有腹泻的儿童中分别检测到4.6(522中的24)和2.6%(428中的11)的HAstV。在1994年10月至1995年3月之间,在墨西哥流通的八种已知HAstV类型中,至少有7种(1至4和6至8型)基因型分型。在腹泻儿童中,HAstV 1和3型最为普遍,尽管并非在所有研究的地区都发现了它们。在墨西哥城,蒙特雷和梅里达发现了8型HAstV。最后,它与1型病毒一样普遍(40%),这表明这种星型病毒比以前公认的更为普遍。没有观察到HAstV感染类型与腹泻症状的存在与否之间的相关性。还研究了肠腺病毒,发现它们分别出现在有症状和无症状的儿童中(2.3(522中的12)和1.4%(428中的6))。

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