Association of the prtF1 Gene (Encoding Fibronectin-Binding Protein F1) and the sic Gene (Encoding the Streptococcal Inhibitor of Complement) with emm Types of Group A Streptococci Isolated from Japanese Children with Pharyngitis

Xiaoming Ma; Hideaki Kikuta; Nobuhisa Ishiguro; Mikio Yoshioka; Takashi Ebihara; Teiko Murai

首页> 外文期刊>Journal of Clinical Microbiology >Association of the prtF1 Gene (Encoding Fibronectin-Binding Protein F1) and the sic Gene (Encoding the Streptococcal Inhibitor of Complement) with emm Types of Group A Streptococci Isolated from Japanese Children with Pharyngitis

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Association of the prtF1 Gene (Encoding Fibronectin-Binding Protein F1) and the sic Gene (Encoding the Streptococcal Inhibitor of Complement) with emm Types of Group A Streptococci Isolated from Japanese Children with Pharyngitis

机译：prtF1基因（编码纤连蛋白结合蛋白F1）和sic基因（编码互补链球菌抑制剂）与日本儿童咽炎儿童分离出的amm型A组链球菌的关联

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A total of 66 clinical isolates of group A streptococci (GAS) were obtained from 66 Japanese children with pharyngitis. The prtF1 gene (encoding fibronectin-binding protein F1) and the sic gene (encoding the streptococcal inhibitor of complement) were present in 51 (77.3%) and 48 (72.7%) of the 66 isolates, respectively. These results indicated that a high prevalence of two virulence genes, prtF1 and sic, is characteristic of GAS in Japan.

机译：从66名日本咽喉炎儿童中获得了66种A组链球菌临床分离株。 prtF1 基因（编码纤连蛋白结合蛋白F1）和 sic 基因（编码补体链球菌抑制剂）分别占51个（77.3％）和48个（72.7％）。）分别分离出66个分离株。这些结果表明，的两个毒力基因 prtF1 和 sic 的高流行是日本GAS的特征。 展开▼

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《Journal of Clinical Microbiology》 |2002年第10期|共3页

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Xiaoming Ma; Hideaki Kikuta; Nobuhisa Ishiguro; Mikio Yoshioka; Takashi Ebihara; Teiko Murai;
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中图分类医学微生物学（病原细菌学、病原微生物学）;

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1. Association of the prtF1 Gene (Encoding Fibronectin-Binding Protein F1) and the sic Gene (Encoding the Streptococcal Inhibitor of Complement) with emm Types of Group A Streptococci Isolated from Japanese Children with Pharyngitis [J] . Xiaoming Ma, Hideaki Kikuta, Nobuhisa Ishiguro, Journal of Clinical Microbiology . 2002,第10期

机译：prtF1基因（编码纤连蛋白结合蛋白F1）和sic基因（编码互补链球菌抑制剂）与日本儿童咽炎儿童分离出的amm型A组链球菌的关联

2. Distribution of fibronectin-binding protein genes (prtF1 and prtF2) and streptococcal pyrogenic exotoxin genes (spe) among Streptococcus pyogenes in Japan. [J] . Hotomi M, Billal DS, Togawa Journal of infection and chemotherapy: official journal of the Japan Society of Chemotherapy . 2009,第6期

机译：在日本化脓性链球菌中，纤连蛋白结合蛋白基因（prtF1和prtF2）和链球菌热原性外毒素基因（spe）的分布。

3. Distribution of fibronectin-binding protein genes (prtF1 and prtF2) and streptococcal pyrogenic exotoxin genes (spe) among Streptococcus pyogenes in Japan [J] . Muneki Hotomi, Dewan S. Billal, Akihisa Togawa, Journal of Infection and Chemotherapy . 2009,第6期

机译：日本化脓性链球菌中纤连蛋白结合蛋白基因（prtF1和prtF2）和链球菌热原性外毒素基因（spe）的分布

4. Computational Analysis of CpG Island Distribution in Human EEF1A2 Gene Encoding a Putative Oncoprotein Implicated in Ovarian and Breast Cancer [C] . Dharmasaroja P. Computer Science and Information Technology - Spring Conference, 2009. IACSITSC '09 . 2009

机译：编码人类EEF1A2基因编码卵巢癌和乳腺癌的假定癌蛋白的CpG岛分布的计算分析。

5. RSF1 and RSF2, nuclear genes encoding proteins required for respiratory growth and mitochondrial DNA maintenance in Saccharomyces cerevisiae. [D] . Lu, Lin. 2003

机译：RSF1和RSF2是编码酿酒酵母中呼吸生长和线粒体DNA维持所需的蛋白质的核基因。

6. Association of the prtF1 Gene (Encoding Fibronectin-Binding Protein F1) and the sic Gene (Encoding the Streptococcal Inhibitor of Complement) with emm Types of Group A Streptococci Isolated from Japanese Children with Pharyngitis [O] . Xiaoming Ma, Hideaki Kikuta, Nobuhisa Ishiguro, 2002

机译：prtF1基因（编码纤连蛋白结合蛋白F1）和sic基因（编码链球菌补体抑制剂）与日本儿童咽炎儿童分离出的A型链球菌的emm型关联

7. Association of the prtF1 Gene (Encoding Fibronectin-Binding Protein F1) and the sic Gene (Encoding the Streptococcal Inhibitor of Complement) with emm Types of Group A Streptococci Isolated from Japanese Children with Pharyngitis [O] . Ma, Xiaoming, Kikuta, Hideaki, Ishiguro, Nobuhisa, 2002

机译：prtF1基因（编码纤连蛋白结合蛋白F1）和sic基因（编码链球菌补体抑制剂）与日本儿童咽炎儿童分离出的A型链球菌的emm型关联

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3. 猪链球菌2型纤连蛋白/血纤蛋白原结合蛋白全基因的克隆及融合表达 [J] . 孙理云 ,范红结 ,陆承平 . 农业生物技术学报 . 2005,第006期

4. 变形链球菌表面蛋白真核表达载体pcDNA3-PAc的构建Ⅲ.变形链球菌表面蛋白PAc编码基因pac的体外扩增 [J] . 刘建国 ,刘天佳 ,周学东 . 贵州医药 . 2003,第008期

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7. 儿童感染青霉素耐药肺炎链球菌的多位点序列分型及青霉素结合蛋白基因突变分析 [A] . 吴健宁 . 2017

1. 肺炎链球菌及其中的荚膜多糖合成方法和SPD-0064基因编码产物及该编码产物的用途 [P] . 中国专利： CN105950511B . 2019.11.05

2. 肺炎链球菌及其中的荚膜多糖合成方法和SPD-0064基因编码产物及该编码产物的用途 [P] . 中国专利： CN105950511A . 2016-09-21

3. Methods to regulate the expression of genes in transgenic plant cells transformed from a stable, plants transformed, molecules of nucleic acids isolated polipeptu00ecdeos maf1 and nmp1,Fusion genes, plant cells processed microbial cells processed, methods of modification of the degree of expression of proteu00ecnas connecting to mfp1 and maf1 in host cells.Methods of obtaining molecules of nucleic acids coding for the proteu00ecnas connecting to mfp1 and maf1 plants and methods for the assessment of at least one compound quu00ecmico as to their capacityAde to inhibit the activity of proteu00ecnas connecting to mfp1 and maf1 plants encoded by nucleic acid molecules. [P] . 外国专利： BR9915307A . 2001-10-23

机译：调节从稳定的，转化的植物的分子中分离出的核酸分子polipept maf1和nmp1的基因在转基因植物细胞中表达的方法，融合基因，植物细胞加工的微生物细胞，修饰基因表达度的方法连接到宿主细胞中mfp1和maf1的蛋白质。获得编码连接到mfp1和maf1植物的蛋白质的核酸分子的方法，以及评估至少一种化合物抑菌能力的方法连接到由核酸分子编码的mfp1和maf1植物的蛋白质的活性。

4. Use of protein factor or nucleic acid encoding the protein factor, for suppressing the expression of genes encoding enzyme with alpha-1,6-fucosyltransferase activity, where the protein factor is e.g. transcription factor KLF15 [P] . 外国专利： FR2956122A1 . 2011-08-12

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5. Isolated nucleic acid fragments encoding an enzyme modifier of vegetable fatty acids associated with the formation of conjugated double joints, fusion genes.Host cells transformed, seeds, oils, methods of modification of the degree of fatty acids with conjugated double unions in a host cell.Methods of producing seed oil containing fatty acids with conjugated double unions in seed plants.Methods for the production of fatty acid modifying enzymes associated with formation of conjugated double joints,Methods of isolation of fragments of nucleic acids and their subfragmentos functionally equivalent encoding an enzyme modifier of vegetable fatty acids associated with the formation of uniS conjugated double, animal feed, methods of improving the quality of the carcass of an animal and complement [P] . 外国专利： BR9913382A . 2001-09-25

机译：编码植物脂肪酸的酶修饰物的分离的核酸片段，与共轭双接头，融合基因的形成有关。转化的宿主细胞，种子，油，在宿主细胞中用共轭双接头修饰脂肪酸程度的方法。在种子植物中生产具有共轭双键脂肪酸的种子油的方法。与共轭双键的形成相关的脂肪酸修饰酶的生产方法;核酸片段的分离方法及其功能等同的编码酶修饰剂的亚片段脂肪酸与uniS共轭双链的形成有关的信息，动物饲料，改善动物car体和补体质量的方法

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Association of the prtF1 Gene (Encoding Fibronectin-Binding Protein F1) and the sic Gene (Encoding the Streptococcal Inhibitor of Complement) with emm Types of Group A Streptococci Isolated from Japanese Children with Pharyngitis

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