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首页> 外文期刊>Journal of Clinical Microbiology >Identification of a Unique HelicobacterSpecies by 16S rRNA Gene Analysis in an Abdominal Abscess from a Patient with X-Linked Hypogammaglobulinemia
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Identification of a Unique HelicobacterSpecies by 16S rRNA Gene Analysis in an Abdominal Abscess from a Patient with X-Linked Hypogammaglobulinemia

机译:通过X连锁低代球蛋白血症患者腹部脓肿中的16S rRNA基因分析鉴定独特的幽门螺杆菌种类。

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A unique Helicobacter species, MZ640285, was isolated from a patient with X-linked hypogammaglobulinemia suffering from recurrent abdominal abscesses and was identified by 16S rRNA gene sequence analysis. In the phylogenetic tree, the isolate fell into a cluster which included Flexispira rappini,Helicobacter bilis, and Helicobacter sp. strain Mainz. Helicobacters are being increasingly recognized as pathogens in immunocompromised hosts. These fastidious bacteria are not easily cultured in the routine diagnostic laboratory, and this is the first report of their identification by 16S rRNA gene sequencing performed directly from a clinical specimen.
机译:从患有腹部反复脓肿的X连锁低球球蛋白血症患者中分离出独特的 Helicobacter 菌种MZ640285,并通过16S rRNA基因序列分析进行鉴定。在系统发育树中,分离株分成簇,包括 Flexispira rappini Helicobacter bilis Helicobacter sp。美因茨菌株。在免疫功能低下的宿主中,越来越多地将幽门螺杆菌视为病原体。这些常规细菌很难在常规诊断实验室中培养,这是通过直接从临床标本直接进行16S rRNA基因测序鉴定它们的首次报道。

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