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首页> 外文期刊>Journal of Clinical Microbiology >blaVIM-2 and blaVIM-7 Carbapenemase-Producing Pseudomonas aeruginosa Isolates Detected in a Tertiary Care Medical Center in the United States: Report from the MYSTIC Program
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blaVIM-2 and blaVIM-7 Carbapenemase-Producing Pseudomonas aeruginosa Isolates Detected in a Tertiary Care Medical Center in the United States: Report from the MYSTIC Program

机译:在美国三级医疗中心检测到的产生blaVIM-2和blaVIM-7碳青霉烯酶的铜绿假单胞菌分离株:MYSTIC计划的报告

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Two Pseudomonas aeruginosa strains resistant to beta-lactams, fluoroquinolones, aminoglycosides, tetracyclines, and carbapenems and susceptible only to polymyxin B (MIC ≤ 2 μg/ml) were identified as part of the Meropenem Yearly Susceptibility Test Information Collection program. Metallo-β-lactamase screening tests were positive, PCR yielded products with blaVIM primers, and sequence analysis revealed blaVIM-7 and blaVIM-2. The isolates had distinct ribotype and pulsed-field gel electorphoresis patterns and appeared independently, remote in time and location, at the same cancer center.
机译:作为美罗培南年度药敏试验信息的一部分,鉴定出了两种对β-内酰胺类,氟喹诺酮类,氨基糖苷类,四环素类和碳青霉烯类耐药的铜绿假单胞菌菌株,它们仅对多粘菌素B(MIC≤2μg/ ml)敏感。收集程序。金属β-内酰胺酶筛选试验呈阳性,用 bla VIM 引物PCR扩增产物,序列分析显示 bla VIM-7 bla VIM-2 。分离株具有独特的核糖型和脉冲场凝胶电泳图谱,并且在同一癌症中心独立出现,时间和位置遥远。

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