...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Clinical Microbiology >Isolation of Nontuberculous Mycobacteria (NTM) from Household Water and Shower Aerosols in Patients with Pulmonary Disease Caused by NTM
【24h】

Isolation of Nontuberculous Mycobacteria (NTM) from Household Water and Shower Aerosols in Patients with Pulmonary Disease Caused by NTM

机译：从NTM引起的肺部疾病患者中分离家用水和淋浴气溶胶中的非结核分枝杆菌（NTM）

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

It has been postulated that susceptible individuals may acquire infection with nontuberculous mycobacteria (NTM) from water and aerosol exposure. This study examined household water and shower aerosols of patients with NTM pulmonary disease. The mycobacteria isolated from clinical samples from 20 patients included M. avium (5 patients), M. intracellulare (12 patients), M. abscessus (7 patients), M. gordonae (1 patient), M. lentiflavum (1 patient), M. fortuitum (1 patient), M. peregrinum (1 patient), M. chelonae (1 patient), M. triplex (1 patient), and M. kansasii (1 patient). One-liter water samples and swabs were collected from all taps, and swimming pools or rainwater tanks. Shower aerosols were sampled using Andersen six-stage cascade impactors. For a subgroup of patients, real-time PCR was performed and high-resolution melt profiles were compared to those of ATCC control strains. Pathogenic mycobacteria were isolated from 19 homes. Species identified in the home matched that found in the patient in seven (35%) cases: M. abscessus (3 cases), M. avium (1 case), M. gordonae (1 case), M. lentiflavum (1 case), and M. kansasii (1 case). In an additional patient with M. abscessus infection, this species was isolated from potable water supplying her home. NTM grown from aerosols included M. abscessus (3 homes), M. gordonae (2 homes), M. kansasii (1 home), M. fortuitum complex (4 homes), M. mucogenicum (1 home), and M. wolinskyi (1 home). NTM causing human disease can be isolated from household water and aerosols. The evidence appears strongest for M. avium, M. kansasii, M. lentiflavum, and M. abscessus. Despite a predominance of disease due to M. intracellulare, we found no evidence for acquisition of infection from household water for this species.
机译：据推测，易感人群可能因接触水和气溶胶而感染了非结核分枝杆菌（NTM）。这项研究检查了NTM肺部疾病患者的家庭用水和淋浴气溶胶。从20例患者的临床样本中分离出的分枝杆菌包括鸟分枝杆菌（5例），胞内分枝杆菌（12例），脓肿分枝杆菌（7例），戈登氏支原体（1例），扁豆支原体（1例）， fortuitum（1名患者），peregrinum（1名患者），chelonae（1名患者），M。Triplex（1名患者）和kansasii（1名患者）。从所有水龙头，游泳池或雨水箱中收集一升水样品和药签。使用Andersen六级级联撞击器对淋浴气溶胶进行采样。对于亚组的患者，进行了实时PCR，并将高分辨率熔解谱与ATCC对照菌株进行了比较。致病性分枝杆菌是从19个家庭中分离出来的。在家庭中鉴定出的物种与患者中发现的物种相匹配，其中有七例（35％）：脓肿支原体（3例），鸟形支原体（1例），戈登支原体（1例），扁豆支原体（1例）和M. kansasii（1例）。在另一名患有脓肿支原体感染的患者中，该物种是从供应她家的饮用水中分离出来的。从气溶胶中生长的NTM包括脓肿支原体（3处），戈氏支原体（2处），堪萨斯分枝（1处），Fortuitum复合体（4处）， M.。 mucogenicum （1个家庭）和 M。 wolinskyi （1个家庭）。可以从家庭用水和气溶胶中分离出导致人类疾病的NTM。证据显示禽鸟支原体，堪萨斯支原体，扁豆支原体和脓肿支原体最强。尽管由于胞内分枝杆菌而引起的疾病占主要地位，但我们没有发现该物种从家庭用水中感染的证据。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号