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PCR-Based Diagnosis of Prosthetic Joint Infection

机译:基于PCR的假肢关节感染诊断

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We performed a meta-analysis to evaluate use of PCR assays for diagnosis of prosthetic joint infection (PJI). The pooled sensitivity and specificity were 0.86 (95% confidence interval [CI], 0.77 to 0.92) and 0.91 (CI, 0.81 to 0.96), respectively. Subgroup analyses showed that use of tissue samples may improve sensitivity, and quantitative PCR and sonication of prostheses fluid may improve specificity. The results showed that PCR is reliable and accurate for detection of PJI.
机译:我们进行了一项荟萃分析,以评估PCR检测法在义肢关节感染(PJI)诊断中的应用。合并的敏感性和特异性分别为0.86(95%置信区间[CI],0.77至0.92)和0.91(CI,0.81至0.96)。亚组分析表明,使用组织样本可以提高敏感性,定量PCR和假体液超声处理可以提高特异性。结果表明,PCR检测PJI可靠,准确。

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