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首页> 外文期刊>Journal of Clinical Microbiology >Investigation of False-Positive Results Given by the QuantiFERON-TB Gold In-Tube Assay
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Investigation of False-Positive Results Given by the QuantiFERON-TB Gold In-Tube Assay

机译:QuantiFERON-TB金管内分析法给出的假阳性结果的调查

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We investigated a sudden increase in the rate of positive QuantiFERON-TB Gold In-Tube results from 10% to 31% at a U.S. academic institution. Direct comparison of the TB antigen tubes with tubes from a different lot number identified that a potential problem with the TB antigen vials in a certain tube lot was the likely cause of the elevated positive rate. The underlying defect remains unknown. This finding warrants refinement of quality control programs by the manufacturer and users.
机译:我们调查了一家美国学术机构的QuantiFERON-TB黄金管内阳性结果的突然增加从10%增加到31%。将TB抗原试管与不同批号的试管直接比较,发现某个试管批次中TB抗原小瓶的潜在问题是阳性率升高的可能原因。潜在的缺陷仍然未知。这一发现保证了制造商和用户对质量控制程序的完善。

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