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首页> 外文期刊>Journal of Clinical Microbiology >Comparative Evaluation of the Bruker Biotyper and Vitek MS Matrix-Assisted Laser Desorption Ionization–Time Of Flight (MALDI-TOF) Mass Spectrometry Systems for Identification of Yeasts of Medical Importance
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Comparative Evaluation of the Bruker Biotyper and Vitek MS Matrix-Assisted Laser Desorption Ionization–Time Of Flight (MALDI-TOF) Mass Spectrometry Systems for Identification of Yeasts of Medical Importance

机译:布鲁克生物识别仪和Vitek MS基质辅助激光解吸电离-飞行时间(MALDI-TOF)质谱系统的比较评价,以鉴定具有医学意义的酵母

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摘要

We report the first comparative evaluation between the Bruker Biotyper MS (BMS) and the Vitek MS (VMS) for the identification of yeasts. The rate of correct identifications at the species level was comparable using the commercial databases (89.8% versus 84.3%; P = 0.712), but higher for BMS using an in-house-extended database (100% versus 84.3%; P = 0.245). Importantly, the rate of misidentification was significantly higher for VMS (1% versus 12.1%; P < 0.0001), including the rate of major errors (0% versus 4.5%; P = 0.0036).
机译:我们报告了布鲁克生物类型分析仪MS(BMS)和Vitek MS(VMS)之间用于酵母鉴定的首次比较评估。使用商业数据库,在物种一级正确鉴定的比率相当(89.8%对84.3%; P = 0.712),但使用内部扩展数据库的BMS的正确鉴定率更高(100%对84.3%; P = 0.245)。重要的是,VMS的错误识别率明显更高(1%比12.1%; P <0.0001),包括主要错误的比率(0%对4.5%; P = 0.0036)。

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