Peaks of Promise and Peril: Screening for Antibiotic Resistance by Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry

Neil W. Anderson

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Peaks of Promise and Peril: Screening for Antibiotic Resistance by Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry

机译：承诺和危险的高峰：通过基质辅助激光解吸电离的飞行时间质谱法筛选抗生素耐药性

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An article in this issue of the Journal of Clinical Microbiology (J.-H. Youn, S. K. Drake, R. A. Weingarten, K. M. Frank, J. P. Dekker, and A. F. Lau, J Clin Microbiol 53:35–42, 2015, http://dx.doi.org/10.1128/JCM.01643-15) describes the use of matrix-assisted laser desorption ionization–time of flight (MALDI-TOF) mass spectrometry for the detection of organisms carrying a bla_KPC-containing plasmid. This powerful and promising application highlights the challenges of using MALDI-TOF mass spectrometry for purposes other than organism identification.

机译：本期《临床微生物学杂志》（J.-H. Youn，SK Drake，RA Weingarten，KM Frank，JP Dekker，and AF Lau，J Clin Microbiol 53：35–42 ，2015年，http：//dx.doi.org/10.1128/JCM.01643-15）描述了使用基质辅助激光解吸电离-飞行时间（MALDI-TOF）质谱法检测携带含有em> bla _{KPC 的质粒。这一功能强大且前景广阔的应用突出了将MALDI-TOF质谱用于生物识别以外的其他挑战。}

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《Journal of Clinical Microbiology》 |2016年第1期|共2页
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Neil W. Anderson;
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中图分类医学微生物学（病原细菌学、病原微生物学）;
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2. Evaluation of combined matrix-assisted laser desorption/ionization time-of-flight and matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry experiments for peptide mass fingerprinting analysis [J] . Da Silva D., Wasselin T., Carré V., Rapid Communications in Mass Spectrometry: RCM . 2011,第13期

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3. Matrix-assisted laser desorption ionization-time of flight mass spectrometry reveals Enterococcus and Enterobacter spp. in major insect species involved in food security with resistance to common antibiotics [J] . Parlapani Foteini F., Kyritsi Maria, Sakka Maria, Journal of pest science . 2020,第1期

机译：基质辅助激光解吸电离 - 飞行时间质谱揭示肠球菌和肠杆菌SPP。在涉及患有常见抗生素的粮食安全的主要昆虫物种中
4. SVM Classification Model of Similar Bacteria Species using Negative Marker: Based on Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry [C] . Jongseo Lee, Yoonsu Shin, Songkuk Kim, IEEE International Conference on Bioinformatics and Bioengineering . 2017

机译：基于负标记的相似细菌物种的SVM分类模型：基于基质辅助的激光解吸/电离飞行时间质谱
5. Laser desorption/laser ionization time-of-flight mass spectrometry instrument design and investigation of the desorption and ionization mechanisms of matrix-assisted laser desorption/ionization. [D] . King, Richard Charles, III. 1994

机译：激光解吸/激光电离飞行时间质谱仪的设计以及基质辅助激光解吸/电离的解吸和电离机理研究。
6. Peaks of Promise and Peril: Screening for Antibiotic Resistance by Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry [O] . Neil W. Anderson 2016

机译：承诺和危险的高峰：通过基质辅助激光解吸电离的飞行时间质谱法筛选抗生素耐药性
7. Commentary: Peaks of Promise and Peril: Screening for Antibiotic Resistance by Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry [O] . Neil W. Anderson 2016

机译：评论：承诺和危险的峰值：通过基质辅助激光解吸电离 - 飞行量谱法筛选抗生素耐药性

Peaks of Promise and Peril: Screening for Antibiotic Resistance by Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry

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