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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Comparison of Clinical and Gram StainDiagnosis Methods of Bacterial VaginosisAmong Pregnant Women in Ethiopia
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Comparison of Clinical and Gram StainDiagnosis Methods of Bacterial VaginosisAmong Pregnant Women in Ethiopia

机译：埃塞俄比亚孕妇细菌性阴道病临床和革兰氏染色诊断方法的比较

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Background:Bacterial Vaginosis (BV) is characterized by an increased thin homogenous white vaginal discharge accompanied by fishy odour and increased vaginal pH. It is associated with different gynecologic and poor obstetric outcome. Bacterial vaginosis can be easily diagnosed by combination of two Amsel?s criteria.Objective:The aim of this study was to evaluate the accuracy of Amsel?s criteria individually or in combination of two for the clinical diagnosis of bacterial vaginosis among pregnant women in Ethiopia.Material and Methods:In this cross sectional study 252 pregnant women were screened for bacterial vaginosis. Vaginal swabs were collected for pH determination, saline wet mount microscopic examination to detect clue cells, KOH preparation for whiff test and Gram-stain evaluation of vaginal flora for diagnosis of bacterial vaginosis by Nugent scoring system. Accuracy of clinical diagnosis using individual and two of Amsel?s criteria was evaluated.Results:The prevalence of BV was 18.3% by Amsel?s two of three criteria and 19.4% Gram by Nugent?s methods. Comparing with Nugent scoring methods, the clinical diagnosis by Amsel?s criteria had sensitivity of 85.7%, specificity of 98%. The most sensitive and specific individual Amsel?s criterion was clue cells. Amsel?s criteria with the lowest sensitivity and specificity were whiff test and vaginal pH respectively. Combination of clue cells with vaginal pH test were the highest in sensitive while whiff test with clue cells were the highest in specificity than the other combined two Amsel?s criteria.Conclusion: Amsel?s criteria diagnosis of bacterial vaginosis can be simplified by using a combination of the two criteria, vaginal pH and clue cells, in settings where time or Gram staining is not available.
机译：背景：细菌性阴道病（BV）的特征是白带稀疏均匀，伴有腥臭味和阴道pH值升高。它与不同的妇科和不良的产科预后相关。结合两个Amsel标准可以轻松诊断细菌性阴道病。目的：本研究的目的是评估埃塞俄比亚孕妇单独或结合两个标准对细菌性阴道病的临床诊断的准确性。材料与方法：在这项横断面研究中，对252名孕妇进行了细菌性阴道病的筛查。收集阴道拭子用于pH测定，盐水湿式显微镜检查以检测线索细胞，KOH制剂用于通气试验以及通过Nugent评分系统对阴道菌群进行革兰氏染色评估以诊断细菌性阴道病。结果：使用Amsel的三个标准中的两个标准，BV的患病率为18.3％，使用Nugent的方法中的革兰氏阳性率为19.4％。与Nugent评分方法相比，根据Amsel标准进行的临床诊断灵敏度为85.7％，特异性为98％。最敏感和具体的个人Amsel标准是线索细胞。 Amsel的灵敏度和特异性最低的标准分别是气味测试和阴道pH值。与其他两种结合在一起的Amsel标准相比，线索细胞与阴道pH测试的结合敏感性最高，而鞭毛细胞与特异性细胞测试的特异性最高。结论：通过使用Amsel标准可以简化细菌性阴道病的诊断。在没有时间或革兰氏染色的环境中，阴道pH和线索细胞这两个标准结合在一起。

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