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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Granulocytic Sarcoma Presenting as an Orbital Mass: Report of Two Cases
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Granulocytic Sarcoma Presenting as an Orbital Mass: Report of Two Cases

机译:表现为眼眶包块的粒细胞肉瘤:两例报告

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Granulocytic sarcoma is a rare variant of a myeloid malignancy, which shows an extra-medullary tumour mass which is composed of my - eloblasts and myeloid precursors with varying degrees of differentiation. It occurs most commonly in bone, periosteum, soft tissue, lymph nodes, and skin; although it can occur anywhere throughout the body. Here, we are reporting two cases of orbital granulocytic sarcoma in children, which presented clinically with proptosis and periorbital swellings, which were first diagnosed by Fine Needle Aspiration Cytology (FNAC). Later, peripheral blood and bone marrow aspirate examinations revealed the evidence of Acute Myeloid Leukaemia (AML). These cases are being documented to demonstrate the utility and diagnostic accuracy of FNAC in evaluation of this entity, in cases of unsuspected AML. Recognition of this rare entity is important, because giving an early aggressive chemotherapy can cause regression of the tumour and thus improve the patient survival
机译:粒细胞肉瘤是髓样恶性肿瘤的罕见变体,显示出髓外肿瘤块,其由成肌细胞和分化程度不同的髓样前体组成。它最常见于骨骼,骨膜,软组织,淋巴结和皮肤。尽管它可以发生在全身的任何地方。在这里,我们报道了两例儿童眼眶粒细胞肉瘤,临床表现为眼角突出和眼眶周围肿胀,这是由细针穿刺细胞学(FNAC)首次诊断出来的。后来,外周血和骨髓抽吸检查发现了急性髓细胞性白血病(AML)的证据。这些案例已记录在案,以证明在未怀疑AML的情况下FNAC在评估此实体时的效用和诊断准确性。识别这种稀有实体非常重要,因为尽早进行积极的化学疗法可导致肿瘤消退,从而提高患者生存率

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