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首页> 外文期刊>Journal of Clinical and Diagnostic Research >A Clinimetric Approach To The Detection And Management Of Vitamin B12 Deficiency Among A Vegan Group In Rural Coimbatore In Tamilnadu
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A Clinimetric Approach To The Detection And Management Of Vitamin B12 Deficiency Among A Vegan Group In Rural Coimbatore In Tamilnadu

机译：泰米尔纳德邦农村哥印拜陀的素食主义者中维生素B12缺乏症的检测和管理的临床方法

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Introduction: Unfortified plant based foods do not contain Vit B12. The deficiency of the vitamin is markedly under-diagnosed and is widespread in the developing countries. Low B12 levels can have profound effects on the patient?s well-being and if this condition is not detected and treated, it can lead to serious irreversible sequelae. There is no gold standard test for diagnosing the B12 deficiency. Materials and Methods: 121 vegans living as a group were assessed for the deficiency of Vit B12 by using a clinimetric tool. Those who were found positive were given parenteral B12 supplementation and were followed up for a three month period. The results were tabulated and analyzed by tests for the significance of the difference in the proportions.Results and Discussion:91(75.2%) of participants were found to be positive for Vit B12 deficiency. The most common (90.1%) presentations were loss of appetite, excess fatigue, mood swings and irritability. The deficiency was significantly higher among the participants who were vegans for more than 5 years. The treatment with parenteral B12 brought about a dramatic improvement in 85.7% of the deficient participants. 93.5% of the participants who were found to be deficient did show a perceptible improvement in well being by the end of three months. Conclusion:Clinimetric approaches to detect Vit B12 deficiency, a majority of which is sub-clinical, as a primary care tool at least for the high risk groups, would definitely help in alleviating a big magnitude of suffering people in the general population.
机译：简介：未经强化的植物性食品不含Vit B12。维生素缺乏症的诊断明显不足，在发展中国家普遍存在。低水平的B12可能对患者的健康产生深远影响，如果不及时发现和治疗这种情况，可能会导致严重的不可逆后遗症。没有用于诊断B12缺乏症的金标准测试。材料和方法：使用斜度仪评估了121个素食主义者的维生素B12缺乏症。发现阳性的患者接受肠胃外B12补充，并随访三个月。结果和讨论通过表格进行了测试，以分析比例差异的显着性。结果与讨论：91名参与者（75.2％）被发现是Vit B12缺乏症阳性。最常见（90.1％）的表现是食欲不振，过度疲劳，情绪波动和易怒。素食超过5年的参与者中，该缺乏症的比例明显更高。肠胃外B12的治疗使85.7％的虚弱参与者显着改善。到三个月末，有93.5％的被发现有缺陷的参与者确实表现出明显的健康改善。结论：用于检测Vit B12缺乏症的临床分析方法（至少是亚临床的）至少作为高风险人群的主要护理工具，肯定会有助于减轻广大普通人群的痛苦。

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