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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Incidence of Japanese Encephalitis in a Tertiary care Centre
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Incidence of Japanese Encephalitis in a Tertiary care Centre

机译：三级护理中心的日本脑炎发病率

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Background: Arbovirus are responsible for a significant number of viral encephalitis cases worldwide. Japanese Encephalitis virus is a mosquito-borne flavivirus that causes a major epidemic of acute encephalitis in humans throughout Asia (5). Scientific literature unequivocally shows the prevalence of Japanese encephalitis in various parts of India (4). In India, cases have been reported from Tamil nadu , Andra Pradesh , Uttar Pradesh , Bihar , Assam , West Bengal , Karnataka , Goa and Maharashtra (6). In recent years, South India has become endemic for the Japanese Encephalitis Virus. While there are reports from other parts of Karnataka which are on the border of Tamil Nadu and Andhra Pradesh, till date, no data is available from South Karnataka. Aim : The present study was conceived to estimate the incidence and clinical profile of Japanese Encephalitis among the patients which were clinically diagnosed with Viral Encephalitis at a tertiary care centre in South India. Material and Methods: One hundred randomly selected cases of clinically diagnosed Encephalitis who were admitted in K.M.C. , Manipal, were included in the study . In - house MAC ELISA was used to detect specific IgM antibodies in the Cerebrospinal fluid (25,26). Results : Anti- JEVirus IgM antibodies were detected in 8 % cases of clinicallydiagnosed encephalitis who were admitted to the K.M.C. Hospital. The mortality rate of the Japanese Encephalitis cases was 12.5 % . No sequalae was recorded in the Japanese Encephalitis cases who survived in our study.
机译：背景：虫媒病毒是导致全球大量病毒性脑炎病例的原因。日本脑炎病毒是一种蚊子传播的黄病毒，在整个亚洲引起人类急性脑炎的主要流行（5）。科学文献清楚地表明，日本脑炎在印度各地流行（4）。在印度，泰米尔纳德邦，安得拉邦，北方邦，比哈尔邦，阿萨姆邦，西孟加拉邦，卡纳塔克邦，果阿和马哈拉施特拉邦都报告了病例（6）。近年来，南印度已成为日本脑炎病毒的地方病。尽管有来自卡纳塔克邦其他地区的报道，这些报道都位于泰米尔纳德邦和安得拉邦的边界，但迄今为止，南卡纳塔克邦尚无数据。目的：本研究旨在评估在印度南部三级护理中心临床诊断出患有病毒性脑炎的患者中日本脑炎的发病率和临床特征。材料和方法：随机选择在K.M.C.医院接受临床诊断的脑炎的一百例病例。 ，Manipal，被纳入研究。内部MAC ELISA用于检测脑脊液中的特异性IgM抗体（25,26）。结果：在接受K.M.C.治疗的临床诊断为脑炎的8％病例中检测到抗JEVirus IgM抗体。医院。日本脑炎的死亡率为12.5％。在我们的研究中幸存的日本脑炎病例中未记录到丝癣菌。

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