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Associated Factors with Male Infertility: A Case Control Study

机译:男性不育相关因素的病例对照研究

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Objective: Sperm analysis is an important step to evaluate and diagnose male?s infertility. The present study aimed to determine associated factors with males? infertility by using semen analysis.Materials and Methods: In this study 96 men were evaluated who attended to the infertility clinics of Ilam province, western Iran between May 2010 to May 2011. Semen analysis was done using the Weili Dynamic Sperm Analysis software adapted to the WHO classification. Based on movement and speed characters, sperms were classified to either A, B, C or D classes. Participants were stratified into two groups that called ?Oligospermia (OS)? with sperm counts of less than 20 million in mL (n=48) and ?Non-Oligospermia (NOS)? with values more than determined cutoff point (n=48). Results: The Mean age ±SD for OS and NOS group were 29.9 ±5.1 y and 31.17 ±5.24 y, respectively (p>0.05). Overall, 62.5% of OS and 31.2% of NOS were clinically infertile (OR=3.6, CI, 1.5-8.5, p=0.01). A significant difference was found between job and live ratio(A+B+C) in NOS group (F=2.8, p<0.05). Conclusion: Prevalence of infertility was higher in the OS men compared to the NOS group. The main risk factors in the OS group were History of Varicocele surgery and residence site of patients that are totally similar to the NOS men. Further case-control studies and clinical trials are recommended to recognize infertility causes in men.
机译:目的:精子分析是评估和诊断男性不育症的重要步骤。本研究旨在确定男性的相关因素?材料和方法:在这项研究中,本研究评估了2010年5月至2011年5月间在伊朗西部伊兰省的不育诊所就诊的96名男性。精液分析是使用适应于男性和女性的Weili动态精子分析软件进行的。世卫组织分类。根据运动和速度特征,将精子分为A,B,C或D类。参与者分为两类,即“少精症(OS)”。精子数量少于2000万毫升(n = 48)和“非少精症(NOS)”?其值大于确定的截止点(n = 48)。结果:OS和NOS组的平均年龄±SD分别为29.9±5.1岁和31.17±5.24岁(p> 0.05)。总体而言,临床上不育的OS占62.5%,而NOS占31.2%(OR = 3.6,CI,1.5-8.5,p = 0.01)。 NOS组的工作与生活比率(A + B + C)之间存在显着差异(F = 2.8,p <0.05)。结论:与NOS组相比,OS男性的不孕症患病率更高。 OS组的主要危险因素是精索静脉曲张手术史和患者的居住地点,与NOS男性完全相似。建议进行进一步的病例对照研究和临床试验,以识别男性不育原因。

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