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Warthin?s Tumour: A Case Report and Review on Pathogenesis and its Histological Subtypes

机译:Warthin的肿瘤:发病机理及其组织学亚型的病例报告与综述

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Warthin?s tumour/ Papillary cystadenoma lymphomatosum (PCL) constitutes a minority of salivary gland neoplasms and it is a monomorphic adenoma which primarily involves the parotid gland. Warthin?s tumour shows multiple cysts that have numerous papillations covered by bilayered columnar and basaloid oncocytic epithelium. The connective tissue portion shows proliferation of follicle- containing lymphoid tissue which necessitates careful distinction for diagnosis. Although, Warthin?s tumour presents as a clinically benign, slow-growing, usually asymptomatic lesion with low rates of recurrences and malignant transformation, but still this tumour is considered unique because of its histological appearance and unknown origin and pathogenesis. Here, we report a case of Warthin?s tumour of five years duration in a 50-year-old male patient in the right parotid gland and also review and discuss various concepts concerning the development of this tumour along with a comprehensive literature on its clinic-pathologic features.
机译:Warthin的肿瘤/乳头状囊腺瘤淋巴瘤(PCL)构成唾液腺肿瘤的少数,它是一种单形性腺瘤,主要累及腮腺。 Warthin瘤显示出多个囊肿,囊肿有许多乳突,被双层柱状和基底类囊泡上皮细胞覆盖。结缔组织部分显示含卵泡的淋巴样组织增生,需要仔细区分以进行诊断。尽管Warthin肿瘤表现为临床上良性,生长缓慢,通常无症状的病灶,复发率和恶性转化率低,但由于其组织学外观以及未知的起源和发病机制,该肿瘤仍被认为是独特的。在这里,我们报告了一名右腮腺的50岁男性患者中持续5年的Warthin肿瘤病例,并回顾和讨论了有关该肿瘤发展的各种概念以及有关其临床的综合文献-病理特征。

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