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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Effect of Platelet Rich Fibrin (PRF) on Peri-implant Soft Tissue and Crestal Bone in One-Stage Implant Placement:A Randomized Controlled Trial
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Effect of Platelet Rich Fibrin (PRF) on Peri-implant Soft Tissue and Crestal Bone in One-Stage Implant Placement:A Randomized Controlled Trial

机译：富血小板纤维蛋白（PRF）对单阶段植入物植入后围植入物软组织和and骨的影响：一项随机对照试验

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Introduction: The viability of Platelet Rich Fibrin (PRF) on enhancement of osseous and associated tissue healing has been substantiated well in literature. However, paucity in the applicability of PRF to enhance peri-implant healing in oral region is not well-corroborated. Purpose: This prospective study evaluated the effect of Platelet PRF on peri-implant tissue response following one-stage implant placement with non-functional immediate provisionalization in maxillary anterior region. Materials and Methods: A Prospective, Randomized Controlled Trial (RCT) was conducted across 20 (15 male, 5 Female) systemically healthy subjects with maintainable oral hygiene. Subjects were broadly divided into two groups i.e. Study group (PRF group) and Control group (Non-PRF group). Twenty standard SLA- AB/AE (alumina oxide blasted/acid etched surface treated) tapered threaded dental implants were randomly placed with and without PRF and immediately provisionalized. The subjects were evaluated clinically and radiographically at baseline (at time of implant placement), one month and three month post-operatively for peri-implant soft tissue and crestal bone responses. Results: At 3 months, all implants remained osseointegrated. The mean marginal bone changes were observed from baseline to 3 months in both groups with lesser changes observed in PRF Group. No significant differences in probing depth and bleeding on probing were noted during follow-up. Conclusion: Within the limitations of this study, PRF could be considered as a healing biomaterial with potential beneficial effect on peri-implant tissue and can be used as a therapeutic adjuvant in clinical scenario of one stage, single tooth implant placement procedure in maxillary anterior region.
机译：简介：文献中充分证实了富血小板纤维蛋白（PRF）在增强骨和相关组织愈合方面的可行性。但是，PRF缺乏增强口腔周围种植体愈合的适用性的证据不足。目的：这项前瞻性研究评估了在上颌前部区域进行无功能立即临时固定的一阶段植入物植入后血小板PRF对植入物周围组织反应的影响。材料和方法：对20名（可维持口腔卫生的）系统健康受试者（15名男性，5名女性）进行了一项前瞻性随机对照试验（RCT）。受试者大致分为两组，即研究组（PRF组）和对照组（非PRF组）。将二十个标准的SLA-AB / AE（经喷砂处理/酸蚀表面处理）的锥形螺纹牙植入物随机放置在有无PRF的情况下，并立即进行临时固定。在基线（植入植入物时），术后1个月和3个月时对受试者进行临床和影像学评估，以评估植入物周围软组织和牙槽骨的反应。结果：3个月时，所有植入物均保持骨整合。两组均从基线到3个月观察到平均边缘骨变化，而PRF组观察到的变化较小。随访期间未发现探查深度和探查出血有明显差异。结论：在本研究的局限性内，PRF可以被视为对植入物周围组织具有潜在有益作用的愈合生物材料，并且可以在上颌前牙区单阶段植入单个牙的临床应用中用作治疗佐剂。

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