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首页> 外文期刊>Journal of Clinical and Diagnostic Research >A Study of Utilization of Antimicrobial Agents in Patients on Ventilator in Intensive Care Unit (ICU) at Tertiary Care Teaching Hospital, India
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A Study of Utilization of Antimicrobial Agents in Patients on Ventilator in Intensive Care Unit (ICU) at Tertiary Care Teaching Hospital, India

机译：印度三级护理教学医院重症监护病房（ICU）呼吸机患者使用抗菌药物的研究

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Objective: To study the use of antimicrobial agents in patients on ventilator in ICU.Materials and Methods: Study was conducted at tertiary care teaching hospital Ahmedabad, India. Total 300 patients admitted in ICU and prescribed antimicrobial agents were included in the study. The data were recorded in preformed Case Record Form (CRF) and were analysed by Z and x2 Test.Result: Patients were divided into group A (patients on ventilator support) and group B (patients without ventilator support). In all the patients antimicrobial agents were prescribed empirically and more than two antimicrobial agents were prescribed in both groups. It was observed that above 60% antimicrobial agents were prescribed according to WHO, National and State Essential Medicine List (EML). Restricted antimicrobial agents (according to antimicrobial policy of tertiary care teaching hospital) were prescribed significantly (p<0.05) higher in group A as compared to group B. Resistance to antimicrobial agents by Pseudomonas aeruginosa and Kleibsella shown significantly (p<0.05) higher in group A as compared to group B. Change of antimicrobial therapy after Culture Sensitivity Test (CST) was significantly (p<0.05) higher in group A as compared to group BConclusion: Number of antimicrobial agents, antimicrobial resistance and change of antimicrobial therapy after CST were higher in patients on ventilator support.
机译：目的：研究ICU呼吸机患者使用抗菌药物的情况。材料与方法：研究在印度艾哈迈达巴德三级护理教学医院进行。该研究共纳入了300名入住ICU和处方抗菌药物的患者。将数据记录在预先形成的病例记录表（CRF）中，并通过Z和x2检验进行分析。结果：将患者分为A组（有呼吸机支持的患者）和B组（无呼吸机支持的患者）。在所有患者中，均根据经验开具了抗菌药物，两组均开具了两种以上的抗菌药物。观察到，根据WHO，国家和州基本药物清单（EML）处方了60％以上的抗微生物剂。与B组相比，A组的受限制抗菌药物（根据三级教学医院的抗菌政策）的处方量显着更高（p <0.05）。结论：抗菌药物的数量，抗菌素耐药性和抗菌药物治疗的改变接受呼吸机支持的患者较高。

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