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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Basaloid Squamous Cell Carcinoma of Tongue: A Report with Emphasis on Immunohistochemistry ZD16-ZD18
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Basaloid Squamous Cell Carcinoma of Tongue: A Report with Emphasis on Immunohistochemistry ZD16-ZD18

机译：舌基底节鳞状鳞癌：免疫组织化学ZD16-ZD18的重点报告。

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摘要

Basaloid Squamous Cell Carcinoma (BScc ) is a rare entity with its histopathological distinction from conventional squamous cell carcinoma. It is frequently considered a high-grade carcinoma with poor prognosis because of higher rate of distant metastases. Here by, we are reporting a case of 39-year-old male with an ulcer on the left lateral border of the tongue since a month. Histopathological examination of incisional biopsy revealed basaloid tumour cell islands accompanied by component of well differentiated squamous cell carcinoma. To reconfirm this incidental finding immunohistochemistry was carried out for Proliferative Cell Nuclear Antigen (PCNA) and pancytokeratin (AE1/AE3) which was positive to conclude diagnosis of BScc . Further p16 staining was done to rule out Human Papilloma Virus (HPV) infection.
机译：基底鳞状鳞状细胞癌（BScc）是一种罕见的实体，其组织病理学与常规鳞状细胞癌有所区别。由于远处转移的发生率较高，常被认为是预后较差的高级癌。到此为止，我们报告了一例39岁的男性，一个月以来在舌头左外侧出现溃疡。切开活检的组织病理学检查显示基底样肿瘤细胞岛伴有高分化鳞状细胞癌的组成部分。为了证实这一偶然发现，对增殖细胞核抗原（PCNA）和全细胞角蛋白（AE1 / AE3）进行了免疫组织化学检查，对确定BScc的诊断是积极的。进行了进一步的p16染色以排除人乳头瘤病毒（HPV）感染。

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