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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Diagnostic Yield of Post-mortem Needle Biopsies and their Spectrum: Experience from a Tertiary Care Hospital
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Diagnostic Yield of Post-mortem Needle Biopsies and their Spectrum: Experience from a Tertiary Care Hospital

机译：验尸针活检的诊断率及其频谱：三级医院的经验

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Conventional autopsy provides important information regarding cause of death, clinico-pathological correlation and is a paramount source of learning. Developing countries have low acceptance rates, denial and limited accessibility for conventional autopsy. Needle autopsy has come up as an alternative to conventional autopsy.Aim: Aim of the study is to analyse postmortem needle biopsies to gauge their utility in lending postmortem diagnosis as well as study its spectrum.Materials and Methods: This is a retrospective study and includes 334 patients. Different organs sampled were liver, lung, kidney, spleen, brain, heart, testis, lip and nose. Clinical data and histopathology slides were retrieved and reviewed by two pathologists.Results: A total of 428 biopsies were received from 334 patients. Forty five (10.5%) biopsies from different organs were non representative. A definite diagnosis was offered in 304 biopsies with an overall diagnostic yield of 79.4%. Liver and kidney biopsies had the maximum diagnostic yield of 89.2% and 69.2%, respectively and most diagnostic category encountered were multiacinar necrosis and fungal infection respectively.Major disagreement (Class 1 and Class 2) between clinical diagnosis and needle autopsy diagnosis was found to be in 21/334 cases (6.3%), where patient would potentially have survived if the clinical diagnosis had been correct.Conclusion: Diagnostic dilemma is a wistful part of medical science. Postmortem needle biopsy has an important role in diagnosis making, improvising the quality of academics and patient care. Level of information and diagnostic yields are high with liver and kidney.
机译：常规尸检提供有关死亡原因，临床病理相关性的重要信息，并且是最重要的学习来源。发展中国家的接受率低，拒绝接受常规尸体解剖，可及性有限。针头尸检已成为常规尸检的替代方法。目的：该研究的目的是分析尸体针活检，以评估其在尸体借诊诊断中的用途以及研究其频谱。材料和方法：是一项回顾性研究，包括334名患者。采样的不同器官是肝，肺，肾，脾，脑，心脏，睾丸，嘴唇和鼻子。两名病理学家检索并审查了临床数据和组织病理学幻灯片。结果：从334例患者中总共接受了428例活检。来自不同器官的四十五（10.5％）个活检没有代表性。 304例活检可明确诊断，总诊断率为79.4％。肝活检和肾活检的最大诊断率分别为89.2％和69.2％，遇到的诊断类别分别是多腺泡坏死和真菌感染。在21/334例患者中（6.3％），如果临床诊断正确，患者将可能存活。结论：诊断难题是医学界的一个重要问题。验尸针活检在诊断过程中起着重要作用，从而提高了学者和患者护理的质量。肝脏和肾脏的信息水平和诊断率很高。

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