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首页> 外文期刊>Journal of bacteriology >THIAMINE AND NICOTINIC ACID: ANAEROBIC GROWTH FACTORS FOR MUCOR ROUXII
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THIAMINE AND NICOTINIC ACID: ANAEROBIC GROWTH FACTORS FOR MUCOR ROUXII

机译:硫胺素和烟酸:MUCOR ROUXII的厌氧生长因子

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Bartnicki-Garcia, S. (Rutgers, the State University, New Brunswick, N. J.), and Walter J. Nickerson. Thiamine and nicotinic acid: Anaerobic growth factors for Mucor rouxii. J. Bacteriol. 82:142–148. 1961.—Mucor rouxii requires preformed thiamine and nicotinic acid for anaerobic growth. Such requirements are not manifested during aerobic incubation. Aerobically, the fungus was shown to be able to synthesize both vitamins. The yeastlike form and the filamentous form of anaerobically grown M. rouxii exhibit the same vitamin requirements. Thiamine can be substituted by its thiazole moiety. Under certain conditions, nicotinic acid was partly substituted by tryptophan, kynurenine, 3-hydroxykynurenine, and 3-hydroxyanthranilic acid. Anaerobically. the fungus (thiamine requiring) was about ten times more susceptible to pyrithiamine antagonism than the same organism grown aerobically (thiamine independent).
机译:Bartnicki-Garcia,S。(罗格斯大学,州立大学,新泽西州新不伦瑞克分校)和Walter J. Nickerson。硫胺素和烟酸:鲁克西姆的厌氧生长因子。 J.细菌。 82:142–148。 1961年。 rouxii 需要预先形成的硫胺素和烟酸来进行厌氧生长。在有氧培养过程中没有表现出这种要求。有氧菌被证明能够合成两种维生素。厌氧生长的 M的酵母样形式和丝状形式。 rouxii 具有相同的维生素需求量。硫胺素可以被其噻唑部分取代。在某些条件下,烟酸被色氨酸,犬尿氨酸,3-羟基犬尿氨酸和3-羟基邻氨基苯甲酸部分取代。厌氧的。真菌(对硫胺素的拮抗作用)对需氧嘧啶胺拮抗作用的敏感性是需氧生长的同一生物(不依赖硫胺素)的十倍。

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