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首页> 外文期刊>Journal of Clinical and Diagnostic Research >ComparativeStudy of Peripheral BloodSmear, QBC and Antigen Detectionin Malaria Diagnosis
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ComparativeStudy of Peripheral BloodSmear, QBC and Antigen Detectionin Malaria Diagnosis

机译：疟疾诊断中外周血涂片，QBC和抗原检测的比较研究

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Rapid diagnosis of malaria is pre-requisite for effective treatment and reducing mortality and morbidity of malaria. In this study, Quantitative Buffy Coat (QBC) was compared with thick and thin peripheral blood smears and malaria antigen test. A total of 387 samples were collected from patients presenting with fever and chills. Malaria was diagnosed in 60, 72 and 56 patients by Leishman staining technique, QBC method and malaria antigen test respectively. The QBC method allowed an additional 12 cases. Thus the prevalence rate of malaria during the study was 18.6%. In 315 patients who were negative by the QBC, malariaantigen test and the Leishman stained smears were also negative for malarial parasite. Although QBC method was superior to the smear for malarial parasite detection, species identification was not possible in 32 cases by this technique.The QBC method has its advantages in terms of speed, sensitivity and ease, especially in an endemic area as ours. The QBC method helps in the diagnosis of jaundice, aplastic anaemia and kala-azar. The QBC system can also be used in the diagnosis of other parasitic diseases such as filariasis. However, Leishman stained thin blood smear still appear superior for species identification.
机译：快速诊断疟疾是有效治疗和降低疟疾死亡率和发病率的先决条件。在这项研究中，定量血沉棕黄层外套（QBC）与厚，薄的外周血涂片和疟疾抗原测试进行了比较。从发烧和发冷的患者中总共收集了387个样本。通过利什曼染色技术，QBC法和疟疾抗原检测分别诊断出60、72和56例患者的疟疾。 QBC方法允许另外12个案例。因此，研究期间的疟疾流行率为18.6％。在315例QBC阴性的患者中，疟疾抗原检测和Leishman染色涂片也对疟原虫为阴性。尽管QBC方法优于疟原虫涂片法，但32种病例无法通过这种技术进行物种鉴定.QBC方法在速度，灵敏度和易用性方面均具有优势，特别是在我们这样的流行地区。 QBC方法有助于诊断黄疸，再生障碍性贫血和黑热病。 QBC系统还可以用于诊断其他寄生虫病，例如丝虫病。但是，利什曼染色的薄血涂片仍显示出对物种鉴定的优越性。

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