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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Carcinoma Stomach: Unwanted Chemotherapeutic Success: ACase Vignette
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Carcinoma Stomach: Unwanted Chemotherapeutic Success: ACase Vignette

机译：胃癌：不需要的化学治疗成功：ACase小插图

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A 45-years-old male, chronic smoker and occasional alcoholic, from Tamenlong district of Manipur was admitted to the department of Surgery, RIMS, Imphal on 19th August, 2011. He was diagnosed as a case of poorly differentiated adenocarcinoma of the stomach located at incissura along the lesser curvature. CT scan of abdomen had revealed para-aortic, aorto-caval and celiac lymphadenopathy. Patient had undergone 5 cycles of neo-adjuvant chemotherapy consisting of 3 weekly course of Oxaloplatin 80mg(D1) + epirubicin 200mg (D1) + Capicitabine 2000mg(D1-D14). After 1 month of chemotherapy, patient then underwent subtotal gastrectomy (modified D2 resection) without any significant peri-operative complication. Surprisingly, the final histopathological report of the resected specimen didn?t reveal any evidence of malignancy in any sections. Role of chemotherapy in gastric cancers has been an adjunct to surgery and the optimal drugs regimen has not been elucidated so far. Till now, very few cases of carcinoma stomach which show pathological complete response have been reported. Our case is such a rare case of pathological complete response following neoadjuvant chemotherapy.
机译：来自曼尼普尔邦塔门隆区的一名45岁男性，慢性吸烟者和偶尔饮酒的人于2011年8月19日被送入Imphal外科，RIMS。他被诊断为一例胃低分化腺癌，位于在切向沿较小的曲率。腹部CT扫描显示主动脉旁，主动脉腔和腹腔淋巴结肿大。患者经历了5个周期的新辅助化疗，包括3周疗程的奥沙铂（80 mg（D1）+表柔比星200mg（D1）+卡西他汀2000mg（D1-D14）。化疗1个月后，患者接受了大体胃切除术（改良的D2切除术），而没有任何明显的围手术期并发症。令人惊讶的是，切除标本的最终组织病理学报告未显示任何切片的任何恶性证据。化学疗法在胃癌中的作用是外科手术的辅助手段，到目前为止，尚不清楚最佳的药物治疗方案。迄今为止，已经报道了极少数显示出病理完全反应的胃癌病例。我们的病例是新辅助化疗后病理完全缓解的罕见病例。

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