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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Embryological Basis and Clinical Correlation of the Rare Congenital Anomaly of the Human Gall Bladder: - ?The Diverticulum? - A Morphological Study
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Embryological Basis and Clinical Correlation of the Rare Congenital Anomaly of the Human Gall Bladder: - ?The Diverticulum? - A Morphological Study

机译：人胆囊罕见先天性异常的胚胎学基础和临床相关性：-“憩室”？ -形态学研究

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Background: Diverticulum of the human gall bladder is an important but distinct anatomical entity with significant clinical implications. It is one of the rarest congenital anomalies of the gall bladder being rarely discussed in literature. This article details the morphology of the diverticula found, along with the embryological basis and clinical significance of this important anatomical and clinical entity.Aim: To study the diverticula found, with respect to their morphology, and ascertain whether they were of congenital or acquired variety.Settings and Design: The present study is a retrospective study carried on hundred cadavers during undergraduate dissection, in the Department of Anatomy, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha, and Department of Anatomy, Subharti Medical College , Meerut during a four year period i.e. 2008-2012 after obtaining necessary permission from institutional ethical committee.Material and Methods: Hundred gall bladder specimens collected from 10% formalin fixed cadavers were studied in detail with regard to their number, position, shapes dimensions and histology.Results: Nine, congenital (true) diverticula were found in one hundred gall bladder specimens. The diverticula were of various shapes and dimensions. They formed pouches on the luminal surface of the gall bladder. Diagnosis of congenital diverticulum was confirmed by histology.Conclusion: In this cadaveric study, solitary diverticulum was found in nine (9%) specimens out of one hundred specimens. Association of diverticulum with non-specific prolonged ailments, acalculus cholecystitis, cholecystitis and cholelithiasis, recurrent cholangitis and carcinoma of gallbladder has been reported in literature. This important anatomical as well as clinical entity poses challenges for radiologists and laparoscopic surgeons during interventional procedures and also should be differentiated from other types of congenital anomalies and pathological states of gall bladder.
机译：背景：人胆囊憩室是重要但截然不同的解剖实体，具有重要的临床意义。这是胆囊最罕见的先天性异常之一，在文献中很少讨论。本文详细介绍发现的憩室的形态，以及该重要解剖和临床实体的胚胎学基础和临床意义。目的：研究发现的憩室的形态，并确定它们是先天性还是后天性设置与设计：本研究是对瓦尔达（Sawangi（Meghe））贾瓦哈拉尔·尼赫鲁医学院（Jawaharlal Nehru Medical College）解剖学系，瓦尔达（Sawangi（Meghe））和密拉特（Meerut）Subharti医学院（Subharti Medical College）解剖系在本科期间解剖的100具尸体进行的回顾性研究。材料和方法：从10％福尔马林固定尸体收集的数百个胆囊标本的数量，位置，形状尺寸和组织学进行了详细研究。在一百个胆囊标本中发现了九个先天性（真实）憩室。憩室具有各种形状和尺寸。它们在胆囊的腔表面上形成囊袋。结论：在尸体研究中，在一百个标本中有九个（9％）标本发现了孤立性憩室。已有文献报道憩室与非特异性长期疾病，小结石性胆囊炎，胆囊炎和胆石症，复发性胆管炎和胆囊癌的关系。这种重要的解剖学和临床实体在介入手术过程中给放射科医生和腹腔镜外科医生带来了挑战，还应与其他类型的先天性异常和胆囊的病理状态区分开来。

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