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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Effect of Ramadan Fasting on Body Weight, (BP) and Biochemical Parameters in Middle Aged Hypertensive Subjects: An Observational Trial
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Effect of Ramadan Fasting on Body Weight, (BP) and Biochemical Parameters in Middle Aged Hypertensive Subjects: An Observational Trial

机译：斋月禁食对中年高血压受试者体重，血压和生化指标的影响：一项观察性试验

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Introduction: Ramadan fasting is a religious obligation which is practised by Muslim population all over the world. However, there is scarcity of scientific literature regarding its effects on health determinants in cardiovascular disturbances like hypertension.Objective: The present study was done to assess the (BP), body weight and serum cholesterol changes over the period of Ramadan fasting in patients with hypertension.Materials and Methods: This prospective observational trial was done on 15 hypertensive subjects who were in the age group of 35 to 65 years, who were determined to complete Ramadan fast. All subjects were on antihypertensive therapy. Outcome measures of (BP), body weight and serum cholesterol were assessed in all the subjects before and after Ramadan month.Results: Mean age of subjects was 44.6 ± 5.62 years. Systolic BP decreased from 148 ± 19.6 to 132.5 ± 17.9 mm of Hg. The decrease of 15.5 units (95% CI: 7.5 to 24.4) was statistically significant (p = 0.0009). Diastolic BP decreased from 90.4 ± 7.8 to 81.1 ± 6.3 mm of Hg. The decrease of 9.3 units (95% CI: 5.7 to 13) was statistically significant (p < 0.0001). There was statistically significant decrease in body weight from 66.6 ± 13 to 65.2 ± 12.7 kg (p < 0.0001). There was no significant difference in serum cholesterol from 187.3 ± 28.9 to 192.7 ± 31.3 mg% (p = 0.37).Conclusion: Hypertensive patients with continuation of their medicines showed a decrease in blood pressure and reduction in body weight at the end of Ramadan fasting duration. However there was no change found in serum cholesterol levels.
机译：简介：斋月斋戒是一项宗教义务，全世界的穆斯林人民都在斋戒。然而，关于其对心血管疾病（如高血压）健康决定因素的影响的科学文献很少。目的：本研究旨在评估斋月期间斋月期间高血压患者的血压（BP），体重和血清胆固醇变化材料与方法：这项前瞻性观察性试验是针对15位年龄在35至65岁之间的高血压受试者进行的，他们被确定可以快速完成斋月。所有受试者均接受降压治疗。在斋月前后，对所有受试者的结果（BP），体重和血清胆固醇进行评估。结果：受试者的平均年龄为44.6±5.62岁。收缩压从148±19.6毫米汞柱降低到132.5±17.9毫米汞柱。减少15.5单位（95％CI：7.5至24.4）具有统计学意义（p = 0.0009）。舒张压从90.4±7.8毫米汞柱降低到81.1±6.3毫米汞柱。下降9.3个单位（95％CI：5.7至13）具有统计学意义（p <0.0001）。体重从66.6±13千克下降到65.2±12.7千克，具有统计学上的显着下降（p <0.0001）。血清胆固醇从187.3±28.9到192.7±31.3 mg ％没有显着差异（p = 0.37）。结论：继续服用药物的高血压患者血压降低，体重减轻。斋月的禁食持续时间。但是，血清胆固醇水平没有变化。

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