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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Comparison of Microbiological Flora in the External Auditory Canal of Normal Ear and an Ear with Acute Otitis Externa MC01-MC04
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Comparison of Microbiological Flora in the External Auditory Canal of Normal Ear and an Ear with Acute Otitis Externa MC01-MC04

机译：正常耳和急性外耳炎MC01-MC04耳外耳道微生物区系的比较

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Introduction: Acute Otitis Externa (AOE) is also known as swimmer?s ear. Investigations initiated during World War II firmly established the role of bacteria in the aetiology of Acute Otitis Externa. Aim: To culture the microbiological flora of the normal ear and compare it with the flora causing AOE and to know the role of normal ear canal flora and anaerobes in the aetiology. Materials and Methods: A prospective observational study was conducted on 64 patients clinically diagnosed with unilateral AOE. Ear swabs were taken from both the ears. Microbiological flora was studied considering diseased ear as test ear and the normal ear as the control. Aerobic and anaerobic cultures were done. Severity of the disease was assessed by subjective and objective scores. Effect of topical treatment with ichthammol glycerine pack was assessed after 48 hours and scores were calculated again. Patients with scores < 4 after pack removal were started on systemic antibiotics and were assessed after seven days of antibiotics course. Data was analysed using Paired t-test, Wilcoxon signed ranks test and Chi-square test. A p-value < 0.05 was considered significant. Results: Pseudomonas aeruginosa (33%) was the most common bacteria cultured from the ear followed by Methicillin Resistant Staphylococcus aureus (MRSA) (18%). Patients with anaerobic organism in the test ear had severe symptoms and needed systemic antibiotic therapy. Conclusion: Most of the cases may respond to empirical antibiotic therapy. In cases with severe symptoms and the ones refractory to empirical treatment, a culture from the ear canal will not be a tax on the patient. This helps in giving a better understanding about the disease, causative organisms and helps in avoiding the use of inappropriate antibiotics that usually result in developing resistant strains of bacteria.
机译：简介：急性外耳炎（AOE）也被称为游泳者的耳朵。第二次世界大战期间发起的调查牢固地确定了细菌在急性外耳炎的病因学中的作用。目的：培养正常耳朵的微生物菌群，并将其与引起AOE的菌群进行比较，并了解正常耳道菌群和厌氧菌在病因中的作用。材料与方法：对64位临床诊断为单侧AOE的患者进行了一项前瞻性观察研究。从两只耳朵上取耳拭子。以患病的耳朵为测试耳朵，以正常的耳朵为对照，研究了微生物菌群。完成好氧和厌氧培养。通过主观和客观评分评估疾病的严重程度。 48小时后评估用ichthammol甘油包进行局部治疗的效果，并再次计算分数。去除包装后评分<4的患者开始使用全身性抗生素，并在抗生素疗程7天后进行评估。使用配对t检验，Wilcoxon符号秩检验和卡方检验分析数据。 p值<0.05被认为是显着的。结果：铜绿假单胞菌（33％）是最常见的从耳朵培养的细菌，其次是耐甲氧西林金黄色葡萄球菌（MRSA）（18％）。测试耳中有厌氧菌的患者有严重症状，需要全身抗生素治疗。结论：大多数病例可能对经验性抗生素治疗有反应。如果症状严重且经验治疗难以治愈，则从耳道进行培养不会对患者造成负担。这有助于更好地了解疾病，病原生物，并避免使用不当的抗生素，因为抗生素通常会导致细菌产生耐药性。

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