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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Concomitant Presence of Carcinoma of Breast in a Patient with Early-Onset Cataract: First Case Report of a Potential Association PD05-PD07
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Concomitant Presence of Carcinoma of Breast in a Patient with Early-Onset Cataract: First Case Report of a Potential Association PD05-PD07

机译：白内障早发患者同时存在乳腺癌：潜在关联PD05-PD07的第一例报告

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摘要

A recent nation-wide population based retrospective cohort study from Taiwan in 2014 suggested a propensity of developing breast cancer in young females with early-onset cataract. We report here a case of a young non-obese female who presented to us with a large lump in the right breast with skin nodules and bilateral painless progressive diminution of vision. Patient was diagnosed to be suffering from locally advanced carcinoma of right breast with axillary metastasis (Stage III B) and bilateral early-onset nuclear cataract. Patient was started on taxane and anthracycline based neoadjuvant chemotherapy and after three cycles of chemotherapy patient showed partial response (?50% reduction of tumour mass). Patient underwent small incision cataract surgery in left eye after the first cycle of chemotherapy. However, the patient was lost before any operative intervention could be done as she died in a road traffic accident. Possible mechanism of development of breast cancer in patients with early-onset cataract is discussed. This is the first reported case of a patient of early?onset cataract developing breast cancer as well as the first reported case of concomitant presence of early-onset bilateral cataract with breast cancer.
机译：2014年来自台湾的一项基于全国人口的回顾性队列研究表明，患有早发性白内障的年轻女性容易患乳腺癌。我们在此报告一例年轻的非肥胖女性，该女性向我们展示了右乳房大结节，皮肤结节和双侧无痛性渐进性视力减退。该患者被诊断为患有右半乳的局部晚期癌，并伴有腋窝转移（III B期）和双侧早发性核性白内障。患者开始以紫杉烷和蒽环类为基础的新辅助化疗，经过三个周期的化疗后，患者显示出部分反应（肿瘤质量降低了50％）。第一次化疗后，患者左眼进行了小切口白内障手术。但是，该患者因道路交通事故死亡，因此在进行任何手术干预之前就迷路了。讨论了早发性白内障患者发生乳腺癌的可能机制。这是第一例报道的早期发病的白内障患乳腺癌的病例，也是第一例报道的同时存在早发的双侧白内障和乳腺癌的病例。

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