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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Prognostic Factors on Survival of Rasoul-e-Akram Hospital Patients with Colorectal Cancer: A Survival Analysis
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Prognostic Factors on Survival of Rasoul-e-Akram Hospital Patients with Colorectal Cancer: A Survival Analysis

机译：Rasoul-e-Akram医院大肠癌患者生存的预后因素：生存分析

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Colorectal Cancer (CRC) also called colon cancer or intestine cancer is characterised by cancerous growth of cells in the rectum, colon and appendix. CRC is the fourth most common form of cancer after skin, gastric, bladder and prostate cancers among Iranian population, since 6-8 people per 10,000 people suffer from this disease.Aim: To evaluate the prognostic factors on survival of patients with CRC, in Rasool-e-Akram Hospital in Tehran, Iran.Materials and Methods: The population under study included patients with CRC, admitted between 30 March 2010 to 29 March 2013, in Rasoul-e-Akram teaching hospital affiliated with Iran University of Medical Sciences, Tehran, Iran. The event was death from CRC and any other cause. Possible prognostic variables were selected from documents. A multivariate Cox regression model was performed to study the concurrent effect of parameters on survival after taking into account the parallel effect of residual factors.Results: In this research 80 patients were studied. With respect to inclusion and exclusion criteria 68 patients were enrolled and data related to 68 patients were exposed to statistical analysis. Median and mean age of patients were equal to 55.5 and 55.0 years, respectively with standard deviation of 13.9 years. Only ?Logarithm of White Blood Cell? showed a significant effect on survival of patients with CRC.Conclusion: The results of our study showed the effect of WBC on survival of patients with CRC. Accordingly the increased one unit of log WBC increased the death hazard by 21.22 times in CRC patient.
机译：大肠癌（CRC）也称为结肠癌或肠癌，其特征在于直肠，结肠和阑尾中细胞的癌性生长。 CRC是伊朗人群中仅次于皮肤癌，胃癌，膀胱癌和前列腺癌的第四大最常见癌症形式，因为每10,000人中有6-8人罹患此病。目的：评估罹患此病的患者的预后因素CRC，位于伊朗德黑兰的Rasool-e-Akram医院。材料与方法：研究对象包括2010年3月30日至2013年3月29日之间在Rasoul-e-Akram教学附属医院的CRC患者。伊朗医学大学，伊朗德黑兰。事件是由CRC和任何其他原因导致的死亡。从文件中选择可能的预后变量。考虑残留因素的平行影响后，使用多变量Cox回归模型研究参数对生存的并行影响。结果：本研究研究了80例患者。关于纳入和排除标准，入组了68例患者，与68例患者相关的数据进行了统计分析。患者的中位年龄和平均年龄分别等于55.5岁和55.0岁，标准差为13.9岁。只有“白细胞对数”？显示对CRC患者生存有显着影响。结论：我们的研究结果显示白细胞对CRC患者生存的影响。因此，增加一单位log WBC对CRC患者的死亡危险增加了21.22倍。

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