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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Detection and Differentiation of Focal Intracranial Calcifications and Chronic Microbleeds Using MRI TC19-TC23
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Detection and Differentiation of Focal Intracranial Calcifications and Chronic Microbleeds Using MRI TC19-TC23

机译：MRI TC19-TC23检测和鉴别局灶性颅内钙化和慢性微出血

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Introduction: Differentiating calcification from chronic micro-bleeds on imaging may have important clinical implications.Aim: The present study aimed to evaluate the role and relative advantages of Magnetic Resonance Imaging (MRI) in the detection and differentiation of intracranial calcifications and chronic microbleeds.Materials and Methods: The retrospective study comprised of 100 patients having either intracranial calcifications or microhaemorrhages selected on the basis of Computerized Tomography (CT) and MRI using predefined criteria. Two independent blinded observers evaluated the images qualitatively and quantitatively. Single pixel values were taken in the circular Region of Interest (ROI) on magnitude SWI, phase Susceptibility Weighted Imaging (SWI) and Diffusion Weighted Imaging (DWI) for quantitative analysis.Results: Fifty patients with 76 focal calcifications and another 50 patients with 245 chronic microbleeds formed part of the study. Overall sensitivity of SWI in detection of calcification was 93.9% with good inter observer agreeability (k= 0.7) on phase SWI. All the chronic microbleeds were seen on SWI but there was only moderate inter observer agreeability in evaluation of signal on phase component (k= 0.5). Average pixel values of calcifications and chronic microbleeds were -312.5±187 SD and 541.9±301.7 SD respectively on phase SWI, (p=0.0001, <0.05).Conclusion: SWI can play a pivotal role in the detection of intracranial calcifications and chronic microbleeds and resolving the ambiguity in their diagnosis.
机译：简介：钙化与慢性微出血的影像学鉴别可能具有重要的临床意义。目的：本研究旨在评估磁共振成像（MRI）在颅内钙化和慢性微血的检测和鉴别中的作用和相对优势。方法：回顾性研究包括100例颅内钙化或微出血的患者，这些患者是根据计算机断层扫描（CT）和MRI使用预先定义的标准选择的。两名独立的盲目观察者对图像进行了定性和定量评估。在SWI幅值，相敏感性加权成像（SWI）和弥散加权成像（DWI）的圆形感兴趣区域（ROI）中获取单个像素值，以进行定量分析。结果：50例患者出现76个局灶性钙化，另外50例患者出现245个钙化慢性微出血是该研究的一部分。 SWI在钙化检测中的整体敏感性为93.9％，在SWI阶段观察者之间具有良好的一致性（k = 0.7）。在SWI上可以看到所有的慢性微出血，但是在评估相位分量信号时，观察者之间只有中等程度的一致性（k = 0.5）。 SWI期钙化和慢性微出血的平均像素值分别为-312.5±187 SD和541.9±301.7 SD，（p = 0.0001，<0.05）。结论：SWI在颅内钙化和慢性微出血的检测中起着关键作用。解决他们的诊断中的歧义。

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