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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Outcome of Critical Pregnant and Postpartum Patients of Swine flu- Experience of Seven Years
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Outcome of Critical Pregnant and Postpartum Patients of Swine flu- Experience of Seven Years

机译：重大孕妇和产后猪流感患者的治疗效果-七年经验

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Pregnancy and postpartum confers four to five fold increased risk for complications and mortality if affected by Swine flu. Swine flu in pregnancy contributes to almost 18-25% of total ICU admissions and high perinatal morbidity and mortality.Aim: The present study was an analysis of the pattern of critical illness and mortality due to Swine flu virus in pregnant and postpartum women.Materials and Methods: It was a retrospective study of all clinically suspected, probable as well as confirmed cases of Swine flu, in pregnancy and postpartum period up to two weeks; who were admitted to Swine flu Intensive Care Unit (ICU) from February 2009 to December 2015. We analyzed the presenting complaints, condition on admission, criteria for admission in ICU, abnormalities in laboratory reports, course of illness and perinatal outcome.Results: In the span of seven years 30 pregnant and 10 postpartum women were admitted in Swine flu ICU. Mortality was 40% (16 out of 40) in pregnant and postpartum women. There were 17 (42.5%) cases which were positive for H1N1 confirmed by Real time-PCR (RT-PCR) and culture. Mean interval of onset of symptoms to start of oseltamivir was four and a half days. Perinatal outcome was poor and only 18% babies were alive after one week of birth.Conclusion: We emphasize that high index of suspicion, early diagnosis, early antiviral therapy and immunization to pregnant women are the key factors which can reduce the complications, ICU admissions and mortality in this group.
机译：如果受到猪流感的影响，怀孕和产后并发症和死亡的风险会增加四到五倍。怀孕中的猪流感占ICU住院总人数的近18-25％，围产期发病率和死亡率高。目的：本研究分析了孕妇和产后因猪流感病毒导致的重症疾病和死亡率材料和方法：这是一项对所有临床怀疑，可能以及确诊的猪流感病例的回顾性研究，涉及怀孕和产后两个星期内;他们于2009年2月至2015年12月被猪流感重症监护病房（ICU）收治。我们分析了提出的投诉，收治情况，ICU收治标准，实验室报告中的异常情况，病程和围产期结局。结果：在7年的时间里，有30名孕妇和10名产后妇女被猪流感ICU收治。孕妇和产后妇女的死亡率为40％（40分之16）。实时PCR（RT-PCR）和培养证实H17N1阳性的病例为17（42.5％）。从开始出现奥司他韦开始的平均症状间隔为四天半。围产期结局很差，出生一周后只有18％的婴儿活着。结论：我们强调怀疑指数高，早期诊断，早期抗病毒治疗和对孕妇免疫是减少并发症的关键因素，该组的ICU入院率和死亡率。

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