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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Vertebral Cryptococcosis Infection in an Immunocompetent Host: A Rare Case Report
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Vertebral Cryptococcosis Infection in an Immunocompetent Host: A Rare Case Report

机译:具有免疫功能的宿主中的椎隐球菌感染:罕见病例报告

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Cryptococcosis is a systemic mycosis caused by yeast like fungus Cryptococcus neoformans. The infection results from inhalation of fungal spores in soil, house dust and in pigeon and other bird excreta. Infection usually occurs in immunocompromised individuals with lung and central nervous system being common sites of involvement. Skeletal involvement usually occurs as a component of disseminated cryptococcosis. Isolated skeletal involvement is rare. Here, the author presents a case of isolated skeletal cryptococcosis in an immunocompetent patient who presented with severe back pain and leg pain. Possibility of Tuberculosis of spine was suggested clinically but histopathology showed cryptococcal granulomas. Patient was HIV seronegative and did not have any other co-morbid conditions. There were no lesions in lung or brain. Because of increasing incidence of crytpococcal infections in immunocompetent hosts it should be included in the differential diagnosis of tuberculosis. Spine and fungal cultures should also be done. In the absence of fungal cultures, histopathological examination including the special stains is useful for diagnosis.
机译:隐球菌病是一种由真菌类新隐球菌引起的系统性真菌病。感染是由于真菌孢子吸入土壤,房屋灰尘以及鸽子和其他鸟类排泄物中。感染通常发生在免疫受损的个体中,其中肺和中枢神经系统是常见的受累部位。骨骼受累通常是弥漫性隐球菌病的一部分。孤立的骨骼受累很少见。在这里,作者介绍了一例患有严重腰背痛和腿痛的免疫功能正常患者的孤立性隐球菌病。临床上提示有脊柱结核的可能性,但组织病理学显示隐球菌肉芽肿。病人是HIV血清阴性,没有其他合并症。肺或脑无病变。由于在具有免疫能力的宿主中引起的冷球菌感染的发生率不断上升,因此应将其纳入结核病的鉴别诊断中。还应进行脊柱和真菌培养。在无真菌培养的情况下,包括特殊污渍在内的组织病理学检查对诊断很有用。

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