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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Histopathological Analysis of Psoriasis in a Study of 24 Cases
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Histopathological Analysis of Psoriasis in a Study of 24 Cases

机译：银屑病的组织病理学分析24例

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As for any other organ system, diagnosis of skin disease involves history and examination. An instant diagnosis can be arrived upon by virtue of visibility of the skin taking into account various visual clues such as scaling, colouring, arrangement and the site of distribution of lesions. Although this appears effortless, the pattern of recognition is complicated while factoring in the individual components and analysing them separately.Aim: To study the varying histopathological findings in cases of psoriasis.Materials and Methods: Prospective study was conducted for two years. All patients who have been clinically diagnosed/suspected and untreated cases of psoriasis attending the Department of Dermatology were taken for the study. Wedge biopsy was taken under local anaesthesia.Results: In the present study, the age group of patients ranged between 8-83 years with 17 of them being males and 07 of them being females. The ratio being 2.4:1 and the mean age was 43 years. The most common histopathological finding was elongated rete ridges, suprapapillary thinning and acanthosis within the epidermis. Munroe microabscess, hyperkeratosis and parakeratosis were the other findings noted within the epidermis. Within the dermis the most common finding was aggregates of lymphocytes which varied from mild to marked along with perivascular infiltration of lymphocytes.Conclusion: Histopathological diagnosis forms the diagnostic tool for the dermatologists to arrive at a conclusion for their differential diagnosis since many skin disorders overlap with clinical presentations of psoriasis. This helps in excluding the differential diagnosis given by the clinician and to arrive at a definite histopathological diagnosis for the betterment of the patient.
机译：至于任何其他器官系统，皮肤病的诊断都涉及病史和检查。考虑到各种视觉线索，例如结垢，着色，排列和病变的分布部位，可以借助皮肤的可见性来进行即时诊断。尽管这似乎很轻松，但在将各个成分考虑在内并分别进行分析时，识别的模式很复杂。目的：研究牛皮癣病例中不同的组织病理学结果。材料和方法：两年将所有在皮肤科就诊且经临床诊断/怀疑为银屑病的未经治疗的银屑病患者纳入研究。结果：在本研究中，患者年龄组介于8-83岁之间，其中男性为17岁，女性为07岁。比例为2.4：1，平均年龄为43岁。最常见的组织病理学发现是表皮内网状脊伸长，乳头上变薄和棘皮症。 Munroe微脓肿，角化过度和角化不全是表皮内的其他发现。在真皮内，最常见的发现是淋巴细胞的聚集，淋巴细胞的聚集程度从轻度到明显，并伴随着血管周围的淋巴细胞浸润。疾病与牛皮癣的临床表现重叠。这有助于排除临床医生给出的鉴别诊断，并有助于明确的组织病理学诊断，以改善患者的病情。

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