ANTIBODIES AGAINST STAPHYLOCOCCUS AUREUS IN NONIMMUNIZED RABBITS

Jay O. Cohen; Glenda S. Cowart; William B. Cherry

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ANTIBODIES AGAINST STAPHYLOCOCCUS AUREUS IN NONIMMUNIZED RABBITS

机译：拟南芥中抗金黄色葡萄球菌的抗体

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Cohen, Jay O. (Communicable Disease Center, Atlanta, Ga.), Glenda S. Cowart, and William B. Cherry. Antibodies against Staphylococcus aureus in nonimmunized rabbits. J. Bacteriol. >82:110–114. 1961.—Antibody against staphylococci was demonstrated in the serum of each of 36 nonimmunized specific-pathogen-free rabbits that were tested. Evidence obtained is in agreement with the proposition that two distinct staphylococcal antibodies are present in the sera from these nonimmunized rabbits. One is responsible for agglutination of Staphylococcus aureus Cowan serotype I, and the other for the formation of a reaction line observed in Ouchterlony plates with soluble antigens of both Cowan serotype I and Cowan serotype III. Fluorescent antibody reagent prepared from preimmune rabbit serum stained some strains of coagulase positive staphylococci, including Cowan's types I and III, and failed to stain any of 14 coagulase negative strains. The sera of rabbits obtained from a commercial source were shown to contain other antibodies for staphylococci in addition to the two found in the sera of specific-pathogen-free rabbits. The data suggested that rabbits from commercial sources have had contact with a great variety of antigens capable of stimulating staphylococcal antibody. Evidence demonstrated that normal rabbit serum from specific-pathogen-free animals of our colony could be used for differentiation of certain staphylococcal strains.

机译：Cohen，Jay O.（乔治亚州亚特兰大，传染病中心），Glenda S. Cowart和William B. Cherry。未经免疫的兔抗金黄色葡萄球菌的抗体。 J.细菌。 > 82： 110-114。 1961年。在测试的36只未免疫的无特定病原体兔子中，每只的血清中均显示出抗葡萄球菌抗体。获得的证据与以下观点一致：来自这些未免疫兔的血清中存在两种不同的葡萄球菌抗体。一个负责金黄色葡萄球菌 Cowan血清型I的凝集，另一个负责在Ouchterlony平板中观察到带有Cowan血清型I和Cowan血清型III的可溶性抗原的反应线的形成。用免疫前兔血清制备的荧光抗体试剂对部分凝固酶阳性葡萄球菌（包括Cowan I型和III型）染色，但未对14种凝固酶阴性菌株中的任何一种染色。从商业来源获得的兔子的血清显示，除了在不含特定病原体的兔子的血清中发现的两种抗体外，还含有其他葡萄球菌抗体。数据表明，来自商业来源的兔子已经与多种能够刺激葡萄球菌抗体的抗原接触。有证据表明，来自我们殖民地的无特定病原体动物的正常兔血清可用于区分某些葡萄球菌菌株。 展开▼

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《Journal of bacteriology》 |1961年第1期|共5页

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Jay O. Cohen; Glenda S. Cowart; William B. Cherry;
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6. ANTIBODIES AGAINST STAPHYLOCOCCUS AUREUS IN NONIMMUNIZED RABBITS [O] . Jay O. Cohen, Glenda S. Cowart, William B. Cherry 1961

机译：拟南芥中抗金黄色葡萄球菌的抗体

7. ANTIBODIES AGAINST STAPHYLOCOCCUS AUREUS IN NONIMMUNIZED RABBITS [O] . Jay O. Cohen, Glenda S. Cowart, William B. Cherry 1961

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ANTIBODIES AGAINST STAPHYLOCOCCUS AUREUS IN NONIMMUNIZED RABBITS

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