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首页> 外文期刊>Journal of bacteriology >Comparisons of F Factors and R Factors: Existence of Independent Regulation Groups in F Factors
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Comparisons of F Factors and R Factors: Existence of Independent Regulation Groups in F Factors

机译：F因子和R因子的比较：F因子中独立调节基团的存在

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The similarity of sex pili mediated by F factors and R(fi+) factors and the ability of R(fi+) factors to control by repression the functioning of pilus genes encoded by the F factor suggested that F factors and R(fi+) factors are closely related. Further comparisons of the episomal properties of F factors and R(fi+) factors, however, indicated many differences. F factors contain information for a restriction system for phages φII and T7. Cells containing R factors are sensitive to these phages. Furthermore, R(fi+) factors do not repress the F factor φII restriction system in cells containing both an R(fi+) factor and an F factor. R factors and F factors are heteroimmune episomes. In addition, an R(fi+) factor in cells containing both an R factor and an F factor does not fully repress the expression of F-factor immunity to an incoming second F factor. R-factor and F-factor replication systems are not identical. Wild-type F-factor replication genes will complement the mutant Fts114lac+ replication genes in cells containing two F factors. The Fts114lac+ episome is retained when these cells are grown at 42 C; however, cells containing an R(fi+) factor and Fts114lac+ lose the Fts114lac+ when grown at 42 C, at the same rate as cells containing only the Fts114lac+. The replication system of the R(fi+) factor will not complement the mutant Fts114lac+ replication system.
机译：F因子和R（fi + ）因子介导的性菌毛的相似性和R（fi + ）因子通过抑制编码的菌毛基因的功能来控制的能力F因子表明F因子和R（fi + ）因子密切相关。 F因子和R（fi + ）因子的附加特性的进一步比较表明存在许多差异。 F因子包含噬菌体φII和T7限制系统的信息。含有R因子的细胞对这些噬菌体敏感。此外，在同时包含R（fi + ）因子和F因子的细胞中，R（fi + ）因子不会抑制F因子φII限制系统。 R因子和F因子是异源免疫附加体。此外，同时包含R因子和F因子的细胞中的R（fi + ）因子不能完全抑制F因子对传入的第二F因子的免疫表达。 R因子和F因子复制系统不相同。野生型F因子复制基因将补充含有两个F因子的细胞中突变的F ts114 lac + 复制基因。当这些细胞在42 C下生长时，它们会保留F ts114 lac + 附加体。但是，包含R（fi + ）因子和F ts114 lac + 的单元格会失去F ts114 lac < sup> + 在42 C下生长，其生长速率与仅包含F ts114 lac + 的细胞的生长速率相同。 R（fi + ）因子的复制系统不会补充突变的F ts114 lac + 复制系统。

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