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首页> 外文期刊>Journal of bacteriology >Significance of HPr in catabolite repression of alpha-amylase.
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Significance of HPr in catabolite repression of alpha-amylase.

机译:HPr在分解代谢抑制α-淀粉酶中的意义。

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CcpA and HPr are presently the only two proteins implicated in Bacillus subtilis global carbon source catabolite repression, and the ptsH1 mutation in the gene for the HPr protein was reported to relieve catabolite repression of several genes. However, alpha-amylase synthesis by B. subtilis SA003 containing the ptsH1 mutation was repressed by glucose. Our results suggest HPr(Ser-P) may be involved in but is not required for catabolite repression of alpha-amylase, indicating that HPr(Ser-P) is not the sole signaling molecule for CcpA-mediated catabolite repression in B. subtilis.
机译:CcpA和HPr是目前仅有的两个与枯草芽孢杆菌整体碳源分解代谢相关的蛋白,据报道,HPr蛋白基因中的ptsH1突变可减轻几个基因的分解代谢抑制。但是,葡萄糖抑制了枯草芽孢杆菌SA003含有ptsH1突变的α-淀粉酶合成。我们的结果表明,HPr(Ser-P)可能参与但不是α-淀粉酶分解代谢阻遏所必需的,这表明HPr(Ser-P)不是枯草芽孢杆菌中CcpA介导的分解代谢物阻遏的唯一信号分子。

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