SSU1 encodes a plasma membrane protein with a central role in a network of proteins conferring sulfite tolerance in Saccharomyces cerevisiae.

D Avram; A T Bakalinsky

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SSU1 encodes a plasma membrane protein with a central role in a network of proteins conferring sulfite tolerance in Saccharomyces cerevisiae.

机译：SSU1编码质膜蛋白，在赋予啤酒酵母亚硫酸盐耐受性的蛋白质网络中起中心作用。

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The Saccharomyces cerevisiae SSU1 gene was isolated based on its ability to complement a mutation causing sensitivity to sulfite, a methionine intermediate. SSU1 encodes a deduced protein of 458 amino acids containing 9 or 10 membrane-spanning domains but has no significant similarity to other proteins in public databases. An Ssu1p-GEP fusion protein was localized to the plasma membrane. Multicopy suppression analysis, undertaken to explore relationships among genes previously implicated in sulfite metabolism, suggests a regulatory pathway in which SSU1 acts downstream of FZF1 and SSU3, which in turn act downstream of GRR1.

机译：酿酒酵母SSU1基因是基于其互补突变的能力而分离的，该突变引起对亚甲硫氨酸中间体亚硫酸盐的敏感性。 SSU1编码一个458个氨基酸的推导蛋白，包含9个或10个跨膜结构域，但与公共数据库中的其他蛋白没有显着相似性。 Ssu1p-GEP融合蛋白位于质膜上。进行多拷贝抑制分析以探索先前与亚硫酸盐代谢有关的基因之间的关系，提出了一条调控途径，其中SSU1在FZF1和SSU3的下游起作用，而SSU3在GRR1的下游起作用。

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《Journal of bacteriology》 |1997年第18期|共4页
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D Avram; A T Bakalinsky;
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6. SSU1 encodes a plasma membrane protein with a central role in a network of proteins conferring sulfite tolerance in Saccharomyces cerevisiae. [O] . D Avram, A T Bakalinsky 1997

机译：SSU1编码质膜蛋白在赋予啤酒酵母亚硫酸盐耐受性的蛋白质网络中起中心作用。
7. SSU1 encodes a plasma membrane protein with a central role in a network of proteins conferring sulfite tolerance in Saccharomyces cerevisiae. [O] . Avram, D, Bakalinsky, A T 1997

机译：SSU1编码质膜蛋白，在赋予啤酒酵母亚硫酸盐耐受性的蛋白质网络中起中心作用。

SSU1 encodes a plasma membrane protein with a central role in a network of proteins conferring sulfite tolerance in Saccharomyces cerevisiae.

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