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Time-averaged serum potassium levels and its fluctuation associate with 5-year survival of peritoneal dialysis patients: two-center based study

机译:腹膜透析患者的平均时间钾水平及其波动与5年生存率的关系:基于两个中心的研究

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The time-averaged serum potassium was more comprehensive to reflect the all-time changes of serum potassium levels during peritoneal dialysis (PD). However, the association of fluctuation of time-averaged serum potassium level with long-time survival of PD patients remains unknown. In this retrospective study, we included 357 incident PD patients in 2 centers from January 1, 2007 to October 31, 2012 with follow-up through October 31, 2014. Our data demonstrated that it was the lower time-averaged serum potassium level rather than baseline of serum potassium level that was associated with high risk of death. Patients with higher standard deviation (SD) had significantly poorer all-cause ( p =?0.016) and cardiovascular mortality ( p =?0.041). Among the patients with time-averaged serum potassium levels below 4.0 mEq/L, a lower mean value was more important than its SD to predict death risk. In contrast, the patients with time-averaged serum potassium levels above 4.0?mEq/L, those with serum potassium SD
机译:时间平均血清钾更全面,以反映腹膜透析(PD)期间血清钾水平的所有时间变化。然而,时间平均血清钾水平的波动与PD患者的长期存活之间的关联仍然未知。在这项回顾性研究中,我们纳入了2007年1月1日至2012年10月31日在2个中心的357例PD患者,并随访至2014年10月31日。我们的数据表明,这是平均时间较低的血清钾水平,而不是血清钾水平的基线与高死亡风险相关。标准差(SD)较高的患者的全因(p =?0.016)和心血管死亡率(p =?0.041)明显较差。在平均血清钾水平低于4.0 mEq / L的患者中,较低的平均值比SD更为重要,以预测死亡风险。相比之下,时间平均血清钾水平高于4.0?mEq / L的患者,血清钾SD

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