• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Scientific reports. >Genetic and molecular characterization of H9N2 and H5 avian influenza viruses from live poultry markets in Zhejiang Province, eastern China
【24h】

Genetic and molecular characterization of H9N2 and H5 avian influenza viruses from live poultry markets in Zhejiang Province, eastern China

机译：来自中国东部浙江省活家禽市场的H9N2和H5禽流感病毒的遗传和分子表征

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Live poultry markets (LPMs) are a key source of reassorted avian influenza viruses (AIVs) because of the density of terrestrial and aquatic poultry and the frequency of AIV infection. H9N2 viruses are prevalent in terrestrial poultry throughout Asia and have been isolated from poultry outbreaks worldwide. They infect both avian and mammalian species and may be significant donors of genetic material to emerging human pathogens. LPMs in Zhejiang Province were surveyed from 2013–2014 for AIVs. Three hundred seventy-four (374) AIV strains were isolated from 3,328 samples. Whole–genome sequencing and phylogenetic analyses were performed. We identified a novel H9N2 virus genotype that had undergone reassortment with gene segments from Qa/HK/G1/97–like, Ck/BJ/1/94–like, and Dk/HK/Y439/97–like viruses. Phylogenetic analyses suggested the H9N2 viruses had undergone reassortments with other AIV subtypes. The results also suggested that two different clades (2.3.2 and 2.3.4.6) of H5 viruses were co–circulating in Zhejiang Province. Given that reassorted H5 AIVs were detected in geese and ducks, it is possible that apparently healthy birds contribute to emerging H5 AIVs. Continued surveillance is required in poultry in eastern China.
机译：由于陆生和水生家禽的密度以及AIV感染的频率，活禽市场（LPM）是重组禽流感病毒（AIV）的主要来源。 H9N2病毒在整个亚洲的陆生家禽中普遍存在，并且已从世界各地的家禽暴发中分离出来。它们感染禽类和哺乳动物，并且可能是新兴人类病原体遗传物质的重要捐助者。 2013年至2014年对浙江省的LPM进行了AIV调查。从3,328个样本中分离出三百七十四（374）个AIV菌株。进行了全基因组测序和系统发育分析。我们确定了一种新的H9N2病毒基因型，该基因型已经与Qa / HK / G1 / 97-like，Ck / BJ / 1 / 94-like和Dk / HK / Y439 / 97-like病毒的基因片段进行了重排。系统发育分析表明，H9N2病毒已与其他AIV亚型重排。结果还表明，浙江省有两个不同的H5病毒进化枝（2.3.2和2.3.4.6）共同传播。考虑到在鹅和鸭中检测到重新分类的H5 AIV，显然健康的禽类可能对新兴的H5 AIV有所贡献。在中国东部的家禽中，需要继续进行监视。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号