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Genetic characterization of subtype H1 avian influenza viruses isolated from live poultry markets in Zhejiang Province, China, in 2011.

机译:2011年从中国浙江省活禽市场中分离到的H1亚型禽流感病毒的遗传特征。

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Nine avian influenza A viruses (AIVs), H1N2 (n?=?2) and H1N3 (n?=?7), were isolated from domestic ducks in live poultry markets in Zhejiang Province, Eastern China, in 2011. All viruses were characterized by whole genome sequencing with subsequent phylogenetic analysis and genetic comparison. Phylogenetic analysis of all eight viral genes showed that the viruses clustered in the Eurasian lineage of influenza A viruses. The hemagglutinin cleavage site of all viruses displayed features of a monobasic cleavage site. Although there was no evidence of re-assortment in subtype H1 AIVs among the avian species and mammalian hosts in this study, continued surveillance is needed considering the important role of the domestic duck in the dissemination and re-assortment of AIVs.
机译:2011年,从华东浙江省活禽市场的家鸭中分离出9种甲型H1N2(n?=?2)和H1N3(n?=?7)禽流感病毒。通过全基因组测序以及随后的系统发育分析和遗传比较。对所有八个病毒基因的系统进化分析表明,这些病毒聚集在甲型流感病毒的欧亚谱系中。所有病毒的血凝素裂解位点均表现出一元裂解位点的特征。尽管在这项研究中没有证据表明禽类和哺乳动物宿主中的H1亚型禽流感病毒发生了重新分类,但考虑到家鸭在禽流感病毒的传播和重新分类中的重要作用,仍需要继续进行监测。

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