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Study protocol to a nationwide prospective cohort study on return to gainful occupation after stroke in Denmark 1996 - 2006

机译：全国范围内队列研究议定书研究丹麦唐氏脑卒中后收益职业研究议定书1996 - 2006年

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Background Successful return to work is regarded as one of the most important outcome factors for working-age post stroke patients. The present study will estimate the effect of various predictors on the odds of returning to work after stroke. Nearly twenty thousand 20-57 year-old stroke patients in Denmark who were gainfully occupied prior to the stroke will be included in the study. Methods/design Stroke patients will be followed prospectively through national registers. Multi-level logistic regression will be used to model the odds of being gainfully occupied ca. two years after the stroke as a function of the following predictors: Age (20-49 years, 50-57 years) gender, occupational class, self-employment (yes; no), onset calendar year (1996, 1997, ..., 2006), diagnosis (subarachnoid haemorrhage; intracerebral haemorrhage; cerebral infarction; stroke, not specified as haemorrhage or infarction) and 'type of municipality' (the variable is set to 1 if the person lived in a municipality which had a brain injury rehabilitation centre at the time of the stroke. Otherwise it is set to 0). Municipalities will be treated as the subjects while individual observations within municipalities are treated as correlated repeated measurements. Discussion Since our follow-up is done through registers and all people in the target population are included, the study is free from sampling bias, recall bias and non-response bias. The study is also strengthened by its size. The major weakness of the study is that it does not contain any stroke severity measures. Thus, it cannot accurately predict whether a particular stroke patient will in fact return to work. The study is, however, quite useful from a public health perspective. It can be used to estimate the proportion of patients in a certain group that is expected to return to work, and thereby provide a comparison material, which e.g. municipalities can use to evaluate their success in returning their stroke patients to work.
机译：背景技术成功回归工作被认为是工作年龄后卒中患者的最重要的结果因素之一。本研究将估计各种预测因子对卒中后返回工作的几率的影响。丹麦近二万千年脑卒中患者，在中风之前被收益占用，将包括在研究中。方法/设计中风患者将通过国家寄存器前瞻性。多级逻辑回归将用于建模有余额占用CA的几率。中风两年后作为以下预测因素的职能：年龄（20-49岁，50-57岁）性别，职业阶层，自雇人士（是;否），发病日历年（1996年，1997年，...... ，2006年），诊断（蛛网膜下腔出血;脑内出血;脑梗塞;中风，未被指定为出血或梗塞）和“城市类型”（如果该人在一个有脑损伤康复的市内居住的人则设定为1在笔划时的中心。否则它设置为0）。市政当局将被视为主题，而市内的个别观察被视为相关的重复测量。讨论以来，我们的后续行动是通过寄存器和目标人口中的所有人进行的，该研究没有采样偏见，召回偏见和非反应偏见。该研究也通过其规模加强。研究的主要弱点是它不含任何中风严重程度措施。因此，它不能准确地预测特定的中风患者是否会恢复工作。然而，这项研究与公共卫生角度相当有用。它可用于估计预期恢复工作的某个组中患者的比例，从而提供比较材料，即，例如市政当局可以用来评估他们的成功，让他们的中风患者工作。

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