• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>BMC Veterinary Research >Transthoracic echocardiography and cardiac biomarkers in healthy captive male and female squirrel monkeys ( Saimiri spp. )
【24h】

Transthoracic echocardiography and cardiac biomarkers in healthy captive male and female squirrel monkeys ( Saimiri spp. )

机译：在健康的俘虏雄性和女性松鼠猴（Saimiri SPP）中的Transthoracic超声心动图和心脏生物标志物

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Echocardiography is the most frequently used non -invasive diagnostic tool to evaluate cardiac anatomy and function in domestic species but increasingly also in non -domestic species, especially since cardiac disease is being recognized as an important cause of death in captive primates. The purpose of this cross -sectional study was to investigate the feasibility of transthoracic echocardiography in healthy squirrel monkeys as well as to provide species specific normal values for standard echocardiographic measurements. A secondary aim was to determine plasma and serum levels of the cardiac biomarkers, N -terminal pro -brain natriuretic peptide (NT -proBNP) and cardiac troponin T (cTnT). Furthermore, a commercial, non -invasive, smartphone -based ECG (AliveCor Vet TM) monitoring device was used to evaluate the heart rate and rhythm and to diagnose possible arrhythmias. In this study, transthoracic echocardiography of 14 squirrel monkeys was performed in right and left lateral recumbency. Similar standard right parasternal and left apical images were obtained as in dogs and cats and normal values for routine two -dimensional, time motion mode and Doppler mode measurements were generated. Thirteen animals were considered healthy and one squirrel monkey was identified with significant aortic dilation and regurgitation and consequently values obtained from this animal were not used when species specific normal values were calculated. NT -ProBNP and cTnT concentrations were available for 7 of the 13 healthy monkeys with NT -proBNP concentrations below detection limit in all animals and a mean cTnT concentration of 0.049?ng/mL. Electrocardiography was performed in all squirrel monkeys. The mean heart rate was 172?bpm. Frequent supraventricular premature beats were diagnosed in the squirrel monkey suffering from significant aortic dilation and regurgitation. This study presents echocardiographic normal values and additional cardiovascular data in anaesthetised Saimiri monkeys, fundamental from both the perspective of zoo animal health care as well as scientific research, since the squirrel monkey is often used as an animal model for human disease.
机译：超声心动图是最常用的非诊断工具，以评估国内物种的心脏解剖和功能，但越来越多地在非族物种中，特别是因为心脏病被认为是俘虏灵长类动物死亡的重要原因。这种跨敏感研究的目的是探讨经静脉超声心动图在健康的松鼠猴中的可行性，并为标准超声心动图测量提供物种特异性正常值。二次目的是测定心脏生物标志物的血浆和血清水平，n末端促血清钠肽（NT -PROBNP）和心肌肌钙蛋白T（CTNT）。此外，用于评估心率和节律并诊断可能的心律失常的商业，非进入智能手机的ECG（AliveCor VET TM）监测装置。在该研究中，在右侧和左侧闭腹部进行了14个静脉猴的Transthoracic超声心动图。获得类似的标准级副胸壁和左顶电视图像，如在狗和猫中获得，并且产生了常规，时间运动模式和多​​普勒模式测量的正常值。考虑着13只动物是健康的，并且用显着的主动脉扩张鉴定一个鼠鼠猴，并且在计算物种特异性正常值时，不使用从该动物获得的重新脉冲，并且在计算出特定的正常值时，没有使用。 NT -PROBNP和CTNT浓度可用于13只健康猴的7个，其中NT -PROBNP浓度低于所有动物的检测限，平均CTNT浓度为0.049≤NG/ mL。在所有松鼠猴中进行心电图。平均心率为172 bpm。常见的Supranculary Future Beats被诊断出患有显着的主动脉扩张和反流的鼠猴。本研究提出了超声心动图正常值和在麻醉的Saimiri猴中的额外心血管数据，从动物园动物保健和科学研究的视角，因为鼠猴常用为人类疾病的动物模型。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号