...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>BMC Infectious Diseases >A case report of a child with probable drug resistant tuberculous pericarditis with a review of challenges involved in diagnosis, treatment and follow up of children with DR-TB pericarditis
【24h】

A case report of a child with probable drug resistant tuberculous pericarditis with a review of challenges involved in diagnosis, treatment and follow up of children with DR-TB pericarditis

机译：具有可能耐药性结核性心包炎的儿童的案例报告，审查了诊断，治疗和跟进患有DR-TB心包炎的儿童的挑战

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

There are unique challenges in the diagnosis and management of multi drug resistant tuberculosis (MDR-TB) in children. It is difficult to obtain confirmatory microbiological diagnosis in TB pericarditis. It is essential to differentiate between drug sensitive and drug resistant forms of TB as it has a major bearing on the regimen used, and inappropriate TB treatment combined with steroid use for pericarditis can lead to deterioration. With lack of samples, the treatment decision relies on the drug resistance pattern of the close contact if available. Therapeutic challenges of MDR-TB management in a child involve use of toxic drugs that need to be judiciously handled. We report a 2?years 4?months old male child who was diagnosed with TB pericarditis and treated based on the resistance pattern of his mother who was on treatment for pulmonary MDR-TB. This 2?years 4?months old male child was diagnosed with TB involving his pericardium. Getting him started on an appropriate regimen was delayed due to the difficulty in establishing microbiological confirmation and drug susceptibility. He was commenced on a regimen based on his mother’s drug resistance pattern and required surgery due to cardiac failure during the course of his treatment. He successfully completed 2?years of therapy. This child’s case demonstrates that despite unique challenges in diagnosis and management of drug resistant extra pulmonary tuberculosis in children, treatment of even complex forms can be successful. The need for high suspicion of MDR-TB, especially when there is close contact with pulmonary TB, careful design of an effective regimen that is tolerated by the child, indications for invasive surgical management of pericarditis, appropriate follow-up and management of adverse effects are emphasised.
机译：儿童多毒性结核（MDR-TB）的诊断和管理具有独特的挑战。难以获得TB心包炎的确认微生物诊断。必须区分TB的药物敏感和耐药形式，因为它对所使用的方案具有重要的轴承，并且不适当的TB治疗与类固醇用于心膜炎的用途可以导致恶化。随着样品缺乏，治疗决策依赖于如果可用的密切接触的耐药图案。儿童MDR-TB管理的治疗挑战涉及使用需要明智地处理的有毒药物。我们报告了2年4年？几个月的男性儿童被诊断出患有Tb心包炎，并根据他母亲的抗性模式治疗，他正在治疗肺部MDR-TB。这2年4年4岁？几个月的男孩被诊断​​为涉及他的心包的结核病。由于建立微生物确认和药物易感性难度，让他开始在适当的方案上延迟。他在治疗过程中基于他的母亲抗药性模式和所需手术的方案开始，他开始了。他成功完成了2年的治疗。该儿童的案例表明，尽管在儿童耐药额外肺结核的诊断和管理方面具有独特的挑战，但甚至复杂形式的治疗可能是成功的。需要高疑似MDR-TB，特别是当与肺结核接触紧密接触时，仔细设计儿童耐受的有效方案，牙动植物炎的侵袭性手术管理的适当随访和管理不良反应强调。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号