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首页> 外文期刊>BMC Infectious Diseases >Endometrial tuberculosis among patients undergoing endometrial biopsy at Tikur Anbesa specialized hospital, Addis Ababa, Ethiopia
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Endometrial tuberculosis among patients undergoing endometrial biopsy at Tikur Anbesa specialized hospital, Addis Ababa, Ethiopia

机译：在埃塞俄比亚亚的斯亚贝巴亚洲亚洲亚洲亚洲亚洲亚洲亚洲亚洲亚洲亚洲省患有子宫内膜患者的子宫内膜结核

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Female genital tuberculosis (FGTB) is known to cause severe tubal disease leading to infertility and its incidence closely parallels with the overall prevalence of tuberculosis (TB) in a community. Its magnitude is underreported because diagnosis is difficult and requires invasive techniques. In this study we determined the prevalence of endometrial tuberculosis and characterized isolates among women who underwent endometrial biopsy for evaluation of various conditions at a Tikur Anbessa Specialized Hospital (TAHS), Addis Ababa, Ethiopia. A cross sectional study was conducted on 152 consecutive gynecologic patients who underwent endometrial biopsy for different gynecologic diseases. Endometrial tissue taken for routine histopathology examination was shared after informed consent was obtained from the patient and subjected to polymerase chain reaction (PCR) and culture for Mycobacterium tuberculosis (Mtb). The prevalence of endometrial TB in this study by IS1081PCR was 4.6% (7/152) while culture proven endometrial TB was 2.6% (4/152). However, histological examination identified only 2/152 (1.3%) endometrial tuberculosis. While all culture proven TB samples were also PCR positive for Mtb, only one histologic proven endometrial TB was culture and PCR positive. All of the four isolates by culture were M. tuberculosis. This study has shown that the magnitude of endometrial TB is fairly high in gynecologic patients visiting outpatient departments for various complaints and PCR detects more cases than culture or Histopathology.
机译：众所周知，雌性生殖器结核（FGTB）导致严重的输卵管疾病导致不孕症，其发病率紧密相似，具有社区中结核病（TB）的总体普遍性。由于诊断困难并且需要侵入性技术，其幅度被报告。在这项研究中，我们确定了子宫内膜结核病的患病率，并表现出在埃涅替亚州伊富米亚的亚·阿巴巴（Tahs），埃塞俄比亚亚的斯·阿巴巴的各种条件下进行子宫内膜活检的妇女患有子宫内膜活检的患者。在152例连续的妇科患者中进行了横截面研究，该妇科患者进行了对不同妇科疾病的子宫内膜活检。在从患者获得知情同意后共享用于常规组织病理学检查的子宫内膜组织，并进行聚合酶链式反应（PCR）和分枝杆菌结核病（MTB）的培养物。本研究中的子宫内膜TB的患病率为1081PCR为4.6％（7/152），而培养已被证明的子宫内膜TB为2.6％（4/152）。然而，组织学检查仅确定了2/152（1.3％）子宫内膜结核。虽然所有文化证明的TB样品也是MTB的PCR阳性，但只有一个组织学证明子宫内膜TB是培养和PCR阳性。培养的所有四分之一的分离物都是结核病。本研究表明，在妇科患者中，妇科患者的子宫内膜结核病的大小相当高，各种投诉和PCR检测到培养或组织病理学的案例。

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