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首页> 外文期刊>BMC Musculoskeletal Disorders >A 3D-printed, personalized, biomechanics-specific beta-tricalcium phosphate bioceramic rod system: personalized treatment strategy for patients with femoral shaft non-union based on finite element analysis
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A 3D-printed, personalized, biomechanics-specific beta-tricalcium phosphate bioceramic rod system: personalized treatment strategy for patients with femoral shaft non-union based on finite element analysis

机译：一种3D印刷，个性化，生物力学特异性β-三胞胎磷酸盐生物陶瓷棒系统：基于有限元分析的股骨轴非联合患者的个性化治疗策略

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Although double-plate fixation (DP), i.e., fixation with a combination of a main lateral plate (LP) and a support medial plate (MP), is a relatively mature method for treating femoral shaft non-union with bone defect causes complications. The purpose of this study was to evaluate LP fixation with a 3D-printed, personalized, biomechanics-specific β-TCP bioceramic rod system (LP?+?3DpbsBRS) as an alternative with less collateral damage. Structure-specific finite element modelling was used to simulate femoral shaft non-union with bone defects and treatment with an LP only as the blank control. Then, the peak von Mises stress (VMS), the VMS distribution, and the plate displacement were determined to compare the effectiveness of LP?+?CBG (cancellous bone grafting), DP?+?CBG, and LP?+?3DpbsBRS under 850?N of axial force. Our results indicated that the peak VMS was 260.2?MPa (LP?+?3DpbsBRS), 249.6?MPa (MP in DP?+?CBG), 249.3?MPa (LP in DP?+?CBG), and 502.4?MPa (LP?+?CBG). The bending angle of the plate was 1.2° versus 1.0° versus 1.1° versus 2.3° (LP?+?3DpbsBRS versus MP in DP?+?CBG versus LP in DP?+?CBG versus LP?+?CBG). The 3DpbsBRS in the LP?+?3DpbsBRS group could replace the MP in the DP?+?CBG group by providing similar medial mechanical support. Furthermore, avoiding the use of an MP provides better protection of the soft tissue and vasculature.
机译：虽然双板固定（DP），即具有主横向板（LP）和支撑内侧板（MP）的组合的固定，但是治疗骨缺损的股骨轴非联合的相对成熟的方法导致并发症。本研究的目的是评估用3D印刷，个性化的生物力学的β-TCP生物陶瓷棒系统（LP？+ 3DPBSBRS）评估LP固定作为替代抵押品损坏的替代方案。特定于结构的有限元建模用于模拟股骨轴非union，仅用LP处理作为空白控制。然后，确定峰值Von误判压力（VM），VMS分布和板位移，比较LP的有效性（包括松散骨移植），DP？+？CBG和LP？3DPBSBRS 850？n的轴向力。我们的结果表明，峰值VMS为260.2？MPA（LP？+？3DPBSBR），249.6？MPA（DP？+？CBG中的MP），249.3？MPA（LP在DP？+？CBG中），和502.4？MPA（ LP？+？CBG）。板的弯曲角为1.2°，与1.1°相比为1.1°（LP？+？3DPBSBRS与DP中的MP与DP？CBG与LP相比，DP？CBG与LP？+？CBG）。 LP中的3DPBSBRS？3DPBSBRS组可以通过提供类似的内侧机械支撑来替换DP + + CBG组中的MP。此外，避免使用MP提供更好地保护软组织和脉管系统。

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