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首页> 外文期刊>Injury >Location of atypical femoral fracture can be determined by tensile stress distribution influenced by femoral bowing and neck-shaft angle: a CT-based nonlinear finite element analysis model for the assessment of femoral shaft loading stress
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Location of atypical femoral fracture can be determined by tensile stress distribution influenced by femoral bowing and neck-shaft angle: a CT-based nonlinear finite element analysis model for the assessment of femoral shaft loading stress

机译：非典型股骨骨折的位置可以通过股骨弓形和颈轴角度影响的拉伸应力分布来确定：基于CT基的非线性有限元分析模型，用于评估股骨轴负荷应力

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Abstract Introduction Loading stress due to individual variations in femoral morphology is thought to be strongly associated with the pathogenesis of atypical femoral fracture (AFF). In Japan, studies on AFF regarding pathogenesis in the mid-shaft are well-documented and a key factor in the injury is thought to be femoral shaft bowing deformity. Thus, we developed a CT-based finite element analysis (CT/FEA) model to assess distribution of loading stress in the femoral shaft. Patients and Methods A multicenter prospective study was performed at 12 hospitals in Japan from August 2015 to February 2017. We assembled three study groups—the mid-shaft AFF group ( n =12), the subtrochanteric AFF group ( n =10), and the control group ( n =11)—and analyzed femoral morphology and loading stress in the femoral shaft by nonlinear CT/FEA. Results Femoral bowing in the mid-shaft AFF group was significantly greater (lateral bowing, p 0.0001; anterior bowing, p 0.01). Femoral neck-shaft angle in the subtrochanteric AFF group was significantly smaller ( p 0.001). On CT/FEA, both the mid-shaft and subtrochanteric AFF group showed maximum tensile stress located adjacent to the fracture site. Quantitatively, there was a correlation between femoral bowing and the ratio of tensile stress, which was calculated between the mid-shaft and subtrochanteric region (lateral bowing, r =0.6373, p r =?0.5825, p Conclusions CT/FEA demonstrated that tensile stress by loading stress can cause AFF. The location of AFF injury could be determined by individual stress distribution influenced by femoral bowing and neck-shaft angle.
机译：摘要由于股骨形态的个体变化引起的引入压力被认为与非典型股骨骨折的发病机制密切相关（AFF）。在日本，关于中轴的发病机制的有法处理的研究是良好的记录，并且损伤的关键因素被认为是股骨轴弯曲畸形。因此，我们开发了基于CT的有限元分析（CT / FEA）模型，以评估股骨轴中的负载应力分布。患者和方法在2015年8月至2017年2月，在日本的12家医院进行了多中心前瞻性研究。我们组装了三个研究组 - 中轴酵母组（n = 12），子系统中的酵母组合组（n = 10），和对照组（N = 11） - 通过非线性CT / FEA分析股骨轴中的股骨形态和装载应力。结果中轴酵素组中的股骨头弯曲明显大（横向弯曲，P 0.0001;前弯曲，P 0.01）。子系统中的股骨颈轴角度明显较小（p 0.001）。在CT / FEA上，中轴和子系统中的轴和子系统酵素组均显示出邻近裂缝部位的最大拉伸应力。定量地，股骨弯曲与拉伸应力的比率之间的相关性，其在中轴和子系统和偏向，辐射，r = 0.6373，pr = 0.5825，P结论CT / FEA方面表现出拉伸应力装载压力可以造成酵素。AFF损伤的位置可以通过受股骨弓形和颈轴角度影响的各个应力分布来确定。

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