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首页> 外文期刊>BMC Pediatrics >What is the impact of the use of transanastomotic feeding tube on patients with esophageal atresia: a systematic review and meta-analysis
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What is the impact of the use of transanastomotic feeding tube on patients with esophageal atresia: a systematic review and meta-analysis

机译：转骨粥样饲料管对食管闭锁患者的影响是什么：系统审查和荟萃分析

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The transanastomotic feeding tube (TAFT) is widely used around the world in patients with esophageal atresia (EA). However, the safety of the use of TAFT is still unknown and remains to be clarified. The following electronic databases were searched: PubMed, EMBASE and Cochrane. Studies comparing outcomes in patients with the use of TAFT (TAFT+) and patients without the use of TAFT (TAFT-) were scrutinized. The quality of included studies was evaluated with the Newcastle-Ottawa scale score. Statistical heterogeneity was assessed using the I2 value. A fixed or random-effect model was applied. Four retrospective controlled studies involving 455 patients were included. The pooled estimates showed that the use of TAFT significantly increased the risk of stricture, with a risk ratio (RR) of 1.83 (95% CI 1.30-2.58; P?=?0.0005). The meta-analyses of other postoperative complications did not show significant differences between TAFT+ and TAFT- group, with a RR of 1.65 (95% CI 0.93-2.93; P?=?0.09) for anastomotic leakage, 0.91 (95% CI 0.34-2.44; P?=?0.85) for sepsis, 1.89 (95% CI 0.22-16.20; P?=?0.56) for tracheomalacia, 0.50 (95% CI 0.13-1.93; P?=?0.31) for gastroesophageal reflux, 1.29 (95% CI 0.28-5.92; P?=?0.74) for wound infection, and 0.97 (95% CI 0.03-36.75; p?=?0.99) for pneumonia. This study demonstrates that the use of TAFT in patients with EA significantly increases the risk of stricture. However, TAFT is not associated with other complications, including anastomotic leakage, sepsis, tracheomalacia, gastroesophageal reflux, wound infection and pneumonia.
机译：转龙膜喂养管（塔夫脱）在食管闭锁（EA）患者中广泛应用于世界各地。但是，使用塔夫夫的使用仍然是未知的并且仍有待澄清。搜索以下电子数据库：PubMed，Embase和Cochrane。在不使用塔夫脱（Taft-）的情况下，研究患者患者患者患者的结果的研究被仔细审查。随着纽卡斯尔 - 渥太华规模得分评估所杂项的质量。使用I2值评估统计异质性。应用了固定或随机效应模型。包括四项涉及455名患者的四项回顾性对照研究。汇总估计表明，塔夫夫斯的使用显着增加了狭窄的风险，风险比（RR）为1.83（95％CI 1.30-2.58; P？= 0.0005）。其他术后并发症的META分析在曲+和曲底组之间没有显示出显着差异，RR为1.65（95％CI 0.93-2.93; p？= 0.09），对于吻合口漏，0.91（95％CI 0.34- 2.44; p？= 0.85）用于败血症，1.89（95％CI 0.22-16.20; p？= 0.56），用于气管癌，0.50（95％CI 0.13-1.93; p？= 0.31）用于胃食管反流，1.29（伤口感染95％CI 0.28-5.92; p？= 0.74）和肺炎的0.97（95％CI 0.03-36.75; p？= 0.99）。本研究表明，在ea患者中使用taft显着提高了狭窄风险。然而，Taft与其他并发症无关，包括吻合口腔渗漏，败血症，气管癌，胃食管反流，伤口感染和肺炎。

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