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Predicting peripartum blood transfusion: focusing on pre-pregnancy characteristics

机译:预测Peripartum输血:专注于妊娠前特征

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BACKGROUND:Obstetric hemorrhage is one of the most common causes of obstetrical morbidity and mortality, and transfusion is the most important management for hemorrhage. The aim of our study was to investigate the pre-pregnancy and pregnancy risk factors for peripartum transfusion.METHODS:Women who delivered a baby from 2010 to 2014 in Korea and participated in the Korean National Health Screening Program for Infants and Children were included. To analyze pre-pregnant risk factors for peripartum transfusion, an additional analysis was done for women who underwent a National Health Screening Examination within 1 year before pregnancy, including maternal waist circumference, body mass index, blood pressure, laboratory tests and history of smoking. Multivariable logistic regression analysis was used to estimate the risk factors for peripartum transfusion.RESULTS:Of the total 1,980,126 women who met the inclusion criteria, 36,868 (1.86%) were transfused at peripartum. In a multivariable regression model, the pregnancy risk factors for peripartum transfusion included maternal age above 35?years [odds ratio (OR): 1.41; 95% confidence interval (CI): 1.32-1.50], preterm birth (OR: 2.39; 95% CI: 2.15-2.65), and maternal hypertension (OR: 2.49; 95% CI: 2.24-2.77). Pre-pregnancy risk factors including fasting glucose level of more than 126?mg/dL (OR: 1.11; 95% CI: 1.02-1.20), current-smoker status (OR: 1.20; 95% CI: 1.06-1.37), and waist-circumference less than 80?cm (OR: 1.18; 95% CI: 1.06-1.30) were independently associated with peripartum blood transfusion.CONCLUSIONS:Several pre-pregnancy and pregnancy risk factors were associated with peripartum blood transfusion. Some identified factors are modifiable before conception, and our study validated peripartum blood transfusion as a form of triage.
机译:背景:产科出血是产科发病率和死亡率最常见的原因之一,输血是出血最重要的管理。我们的研究目的是探讨Peripartum Transfusion的妊娠前和怀孕危险因素。包括从2010年到2014年在韩国送到2010年和参加韩国国家卫生筛查计划的婴儿和儿童的妇女。为了分析妊娠期输血预期危险因素,为在怀孕前1年内进行全国健康筛查检查的妇女进行了额外的分析,包括产妇腰围,体重指数,血压,实验室测试和吸烟历史。多变量逻辑回归分析用于估计Peripartum输血的危险因素。结果:纳入普及的纳入标准的1,980,126名妇女中,将36,868(1.86%)在Peripartum中生效。在多变量的回归模型中,Peripartum输血的妊娠风险因素包括35岁以上的孕产妇年龄?年龄(赔率比(或):1.41; 95%置信区间(CI):1.32-1.50],早产(或:2.39; 95%CI:2.15-2.65)和母体高血压(或:2.49; 95%CI:2.24-2.77)。妊娠前的危险因素,包括禁食葡萄糖水平超过126毫克/米/ dl(或:1.11; 95%CI:1.02-1.20),当前吸烟者状态(或:1.20; 95%CI:1.06-1.37),和腰围小于80?cm(或:1.18; 95%ci:1.06-1.30)与Peripartum血液输血独立相关。结论:几种妊娠前和怀孕危险因素与Peripartum输血有关。一些已识别的因素是可修改的概念之前,我们的研究验证了作为种类形式的Peripartum输血。

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