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Long-Term Follow-Up after Conservative Surgical Treatment of Odontogenic Myxoma: A Case Report and Literature Review

机译:长期随访后幼儿遗传学肌瘤保守疗法:案例报告和文献综述

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Odontogenic myxoma (OM) is a relatively rare, benign odontogenic tumor with locally aggressive behavior, but it is a nonmetastasizing neoplasm of the jaw bones. Although radical resection with an appropriate surgical margin is recommended, emerging evidence has suggested that a more conservative approach will result in acceptable recurrence rates with less morbidity if careful long-term follow-up is provided. A 56-year-old Japanese man with odontogenic myxoma of the left mandible was conservatively treated by surgical enucleation and curettage because he desired functional and cosmetic preservation. During a follow-up period of 100 months, the patient has remained clinically and radiologically free of recurrence. As far as we can ascertain, 20 reports published after 1990 described 37 patients with mandibular OM that had been treated by conservative surgery. Tumors recurred during a mean follow-up of 49.2±42.8 months in 7 (18.9%) patients, and only one of five patients who were followed up for over 100 months developed recurrence. The rate of recurrence decreased from 24.0% to 8.3% when follow-up exceeded 60 months. Although enucleation and curettage have proven effective, the risk of recurrence remains considerable and long-term follow-up is indispensable. More evidence of long-term outcomes after conservative surgery for OM is needed.
机译:幼儿植物肌瘤(OM)是一种相对罕见的良性成牙癌,具有局部侵蚀性行为,但它是颌骨的非甜食肿瘤。尽管建议具有适当的外科裕度的激进切除,但新兴的证据表明,如果提供了仔细的长期随访,则更保守的方法将导致可接受的复发率,如果提供仔细的长期随访,则会降低发病率。一个56岁的日本人,左下颌骨的幼儿肌瘤是由手术的enucleation和刮宫治疗的,因为他所期望的功能和化妆品保存。在随访期间为100个月,患者在临床上并没有复发临床和放射性。据我们所知,1990年后发表的20个报告描述了37例由保守手术治疗的下颌OM患者。在7例(18.9%)患者的平均随访期间重复肿瘤,患者只有五个月超过100个月的五个患者中只有100个患者。随访60个月后,复发率从24.0%降至8.3%。虽然Enucleation和刮宫已经证明有效,但复发的风险仍然是相当大的,长期随访是必不可少的。需要在保守的手术中进行长期成果的更多证据。

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