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首页> 外文期刊>Case Reports in Otolaryngology >Bilateral Facial Paralysis and Deafness in a Child Treated for Acute Lymphoblastic Leukemia
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Bilateral Facial Paralysis and Deafness in a Child Treated for Acute Lymphoblastic Leukemia

机译：对急性淋巴细胞白血病治疗儿童的双侧面部瘫痪和耳聋

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Involvement of the ear and temporal bone in acute leukemias are uncommon. We report a case of atypical mastoiditis with bilateral facial paralysis in a child diagnosed with Acute Lymphoblastic Leukemia (ALL). A 20-month-old male child was diagnosed with ALL and developed otorrhea unresponsive to antimicrobial treatment during the first week of chemotherapy followed by hearing loss, loss of balance, and bilateral facial paralysis. A CT scan of the mastoids showed cortical erosion of the temporal bone and presence of soft tissue contents filling the mastoid cells and external auditory canal bilaterally. Mastoidectomy was performed to collect material for analysis. Histopathologic examination of the material revealed an active chronic inflammatory process, with a moderate amount of plasma cells. Chemotherapy was reintroduced 3 weeks after the surgical procedure, and progressive improvement of otorrhea and imbalance was noted. Grade III House–Brackmann peripheral facial paralysis persisted on 6-month follow-up, and the patient is in rehabilitation program.
机译：耳朵和颞骨在急性白血病中的参与罕见。我们举报了患有急性淋巴细胞白血病（全部）的儿童双侧面部瘫痪的非典型乳突炎。一个20个月大的男孩被诊断​​出患有全部，并在化疗的第一周内没有反应抗菌治疗，然后通过听力丧失，平衡丧失和双侧面部瘫痪。乳突的CT扫描显示了颞骨的皮质侵蚀和软组织内容物的存在，软组织内容物填充了乳突细胞和外耳道的双侧。进行乳腺切除术以收集用于分析的材料。该材料的组织病理学检查显示了活性慢性炎症过程，具有中等量的血浆细胞。在外科手术后3周内再介绍化疗，并注意到耳聋和失衡的逐步改善。 III级House-Brackmann外周面部瘫痪在6个月的随访中持续存在，患者处于康复计划中。

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