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首页> 外文期刊>Case Reports in Otolaryngology >Successful Treatment of a Mixed Neuroendocrine-Nonneuroendocrine Neoplasm of the Colon with Metastases to the Thyroid Gland and Liver
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Successful Treatment of a Mixed Neuroendocrine-Nonneuroendocrine Neoplasm of the Colon with Metastases to the Thyroid Gland and Liver

机译：成功治疗结肠的混合神经内分泌 - 非积分内部肿瘤与转移到甲状腺和肝脏

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Patients with mixed neuroendocrine-nonneuroendocrine neoplasms (MiNENs) of the colon have poor prognosis. Herein, we report a patient with MiNEN of the colon with metastases to the liver and the thyroid gland, with long-term survival. A 45-year-old man presented with anterior neck swelling. Histopathological examination of the thyroid tumor revealed neuroendocrine carcinoma (NEC), suggesting that a primary NEC in another organ had metastasized to the thyroid gland. Computed tomography to identify a primary NEC revealed two tumors: one in the liver and one in the transverse colon. A biopsy revealed that the histopathology of the liver and colon tumors was NEC and adenocarcinoma, respectively. Thereafter, the patient underwent surgical resection of the colon tumor and was finally diagnosed as colon MiNEN with metastases to the thyroid and liver. The surgical resection of the metastatic liver tumor was performed after several courses of systemic chemotherapy, and the patient survives presently without any recurrence for approximately seven years after the diagnosis. Surgical resection of each metastatic lesion combined with systematic chemotherapy apparently improved the prognosis of MiNEN of the colon with distant metastases.
机译：结肠混合性神经内分泌 - 非通量内分泌瘤的患者具有差的预后差。在此，我们向肝脏和甲状腺转移报告患有结肠癌的患者，长期存活。一个45岁的男子患有前颈肿胀。甲状腺肿瘤的组织病理学检查揭示了神经内分泌癌（NEC），表明另一个器官中的主要NEC已向甲状腺转移。计算断层摄影术以识别主要NEC显示出两种肿瘤：在肝脏中的一个，在横向结肠中的一个。活检显示，肝脏和结肠肿瘤的组织病理学分别是NEC和腺癌。此后，患者接受了结肠肿瘤的手术切除，并且最终被诊断为甲状腺和肝脏转移的结肠开关。在几种全身化疗的几个课程后进行转移性肝肿瘤的手术切除，并且诊断后患者患者在没有任何复发的情况下存活。每种转移性病变的外科切除与系统化疗结合显然改善了结肠癌的预后与远处转移。

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