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A Pink Herring in the Colon: A Case Report of Eosinophilic Colitis Masking Invasive Adenocarcinoma of the Colon

机译:冒号中的粉红色鲱鱼:嗜酸性结肠炎掩盖侵袭性腺癌的案例报告

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Eosinophilic colitis is an inflammatory condition in which the wall of the colon becomes infiltrated by eosinophils which stain densely pink on microscopy. It is an uncommon clinical entity which has a long list of differential diagnoses. We present a case of a patient whose biopsy at colonoscopy revealed eosinophilic colitis which led to a delay in the diagnosis and subsequent treatment of colon cancer. A 35-year-old male presented with a six-week history of right lower quadrant abdominal pain associated with diarrhoea and weight loss. Colonoscopy showed an inflamed cecum; computed tomography revealed a small ascitic fluid collection in the right iliac fossa. Biopsy showed eosinophilic colitis, and he was treated conservatively with albendazole and mesalamine. The patient failed to improve over the following month with continued weight loss. A repeat CT scan showed a right iliac fossa mass. A right hemicolectomy was performed with histopathology from the specimen showing mucinous adenocarcinoma. Eosinophilic colitis can mask colon cancer and should be considered a diagnosis of exclusion.
机译:嗜酸性结肠炎是一种炎症状况,其中结肠壁被嗜酸性粒细胞渗透,嗜酸性粒细胞在显微镜下染色密度粉红色。它是一种罕见的临床实体,具有长期差异诊断。我们提出了一种患者的患者,其结肠镜检查的活组织检查显示嗜酸性结肠炎,其导致诊断和随后治疗结肠癌的延迟。一名35岁的男性呈现出六周的右下象限腹痛,与腹泻和减肥相关。结肠镜检查显示发炎的盲肠;计算机断层扫描揭示了右髂骨中的小腹水收集。活组织检查显示嗜酸性结肠炎,他守护地治疗了苯唑和梅萨明胺治疗。患者未能在持续体重减轻后未能改善。重复CT扫描显示出右髂骨窝量。用来自显示粘液腺癌的标本的组织病理学进行右半聚切除术。嗜酸性结肠炎可以掩盖结肠癌,应该被认为是排除的诊断。

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